Protein Alignment CG11873 and Bicral

DIOPT Version :9

• Sequence 1: NP_001263051.1
• Gene: CG11873 / 43435
• FlyBaseID: FBgn0039633
• Length: 3003
• Species: Drosophila melanogaster
• Sequence 2: NP_001100358.1
• Gene: Bicral / 301235
• RGDID: 1305680
• Length: 1078
• Species: Rattus norvegicus
• Alignment Length: 1329
• Identity: 251/1329 - (18%)
• Similarity: 419/1329 - (31%)
• Gaps: 422/1329 - (31%)

  Fly  1328 KLSG-QVTHPASSMLGMTSTTTTMSTMKPPANLPAKQNEVVSFPQ--LPLNSQVLIQQQPMISAQ 1389
            |.|| .||:...|.....|.....:...|.::|....|::...|.  |||.|.:...:..:.|:.
  Rat    29 KSSGDDVTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLASSLQFLEDELESSP 93

  Fly  1390 LQPQL---QPVTVPVSLPTQPVPIPSPAPAPQL---ANNGQQRYIALPPIDPTTQQLFC-LNSVT 1447
            | |.|   ||..: :....|...|.....|.:.   |:.|..:..|...:.|::...|. .::|:
  Rat    94 L-PDLSEDQPFDI-LQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVS 156

  Fly  1448 NQITAMSAGQTAASIGPTERLLIAPAGINAQQLAQCLQLGQLHFNDVNPLPAQQQQQQVATTSSS 1512
            |.     :|||...||.|.    .|.|.:.......:|.|.:              |.|.
  Rat   157 NY-----SGQTLQPIGVTH----VPVGASFASNTVGVQHGFM--------------QHVG----- 193

  Fly  1513 MTLSMPLRPQPPQQQIVHPIQPITNGLAITTTASSTLTTTTS---TTSLTTVTKQVANVAPIIDQ 1574
              :|:|.:..|...||               :.|..:....|   ..|:.|:..        :|.
  Rat   194 --ISVPSQHLPNSSQI---------------SGSGQIQLIGSFGNQPSMMTINN--------LDG 233

  Fly  1575 SKAKLE-PAKAATSGAGGGAVVKKK----------PVRKPKATPTNASELANLKNASVVKPMPKL 1628
            |:..|: ..:.|.|...||.:|.::          |...|.|.|....  .|..|.....|:..:
  Rat   234 SQIILKGSGQQAPSSVSGGLLVHRQTPNGNSLFGNPTSSPGAQPVTVP--FNSTNFQASLPVHNI 296

  Fly  1629 DPLSQK---PNNNPVQI-VQPN-VASGKQMIVVGSSSCTTTTTTTMSASIQPFQTTSGTKLVGVT 1688
              :.|:   ||:|.|.| :||. :..|:|           :|....|..:|......|......:
  Rat   297 --IIQRGLAPNSNKVPINIQPKPIQMGQQ-----------STYNVNSLGLQQHHVQQGISFASAS 348

  Fly  1689 VPM-QQQQPTGTAAILQQQQQQRTSFSLTATTVATPAPMPSPTVASGVSQLQMQQLPSQQAQQQL 1752
            .|. ....|..:..|:.||..::              |:.|..|:|....:.:.. |..|..
  Rat   349 SPQGSVVGPHMSVNIVNQQNARK--------------PVTSQAVSSAGGSIVIHS-PMGQPH--- 395

  Fly  1753 QPQQQQQLHAPKQQQPQPNTVSRVQTI--QL--TPQMQQIFKQVQMQIQFLTIKLQNKSTFL--- 1810
              ..|.|...|.......|:|..||||  ||  |...|.|..||..:...|.   :|.|..|
  Rat   396 --TPQSQFLIPTSLSVSSNSVHHVQTINGQLVQTQPSQLISGQVASEHVMLN---RNSSNMLRTN 455

  Fly  1811 -PVSPE-----------IDSATIAAYNKPMTDAEINLALQRLFAEQHRI-LASGKEVPTPEGMLP 1862
             |.:.:           :...|.|....|:.   :|.|..::...|..: .||...:....|...
  Rat   456 QPYAGQMLNNQSAAVQLVSGQTFATSGSPVI---VNHASPQIVGGQMPLQQASPTVLHLSPGQSS 517

  Fly  1863 TANGTGGFSLMPQPVQQQQQQQQQQLQSTVPEPLK--TIVPANVVQPNNHSSTPAGAATSGATTA 1925
            .:.|..||:.|..             .|::..|.:  .:..|:...|.      .|.|.....:.
  Rat   518 VSQGRPGFATMAS-------------VSSMSGPARFPAVSSASTAHPT------LGPAVQSGASG 563

  Fly  1926 ANIQQNITQRIHIYPMQHQQQQQQQQQQQQQQPQHQQQQPQHQLQQTGAKPKQAQPKPPPQQEQQ 1990
            :|.                                           ||.:..||...|.|
  Rat   564 SNF-------------------------------------------TGDQLTQANRTPVP----- 580

  Fly  1991 SQLQIKPKEPANRSKVTSQQLQQNPQPPNGTINMLPQKVSMMPVVQQQQQQQPQQHQQQPMLNKS 2055
              :.:..:.|.:.||                   .|..:|..|..|||
  Rat   581 --VSVSHRLPVSASK-------------------SPSTLSSTPGTQQQ----------------- 607

  Fly  2056 GPPPLIFASSTNMLSNSNSNNLHNSNSAMQVNNMLPLPPLQPQQQPQPQLQQPPTP-ILPPVAPT 2119
                 .|..:....                :|...|:|...|..:....|:||..| :|....|.
  Rat   608 -----FFCQAPKKC----------------LNQTAPIPTPIPTSKTTDSLRQPQIPGLLSTALPG 651

  Fly  2120 MAMG--VAPGPMGNLVPSLP-TIPSLPLYMPSKMDEMPTQK----PKIARLSLFVRQLEVDQESC 2177
            ...|  :.|.|:|...|... ::.|.|.....::|....||    .::.:.:..::||:.||...
  Rat   652 QDCGSKIMPAPLGTTQPQQENSVGSSPSQTAVQVDSHSGQKRPAAKQLTKGAFILQQLQRDQAHA 716

  Fly  2178 LKPDYVKPFRTKDEAVKRLIRYHCMHENDVELPSDE-----DEEFESTALEFQDKFRQLNGKFQE 2237
            :.|| ...||:..:.|:||:.||....:   :|::|     |.|||..|.:...:...:..|::.
  Rat   717 VTPD-KSQFRSLTDTVQRLLSYHVCQGS---MPTEEDLSKVDSEFEEVATQLLKRTHAMLNKYRS 777

  Fly  2238 ILMQESTLPHRTSELLQMQQLMIDDLKGEINEIRTAEKELEQQLKEEQTSEKSTAESDVLSEAKV 2302
            :|::::...:.::|:     :|||.:   .|:...|....:::|   ...:....::|.....|:
  Rat   778 LLLEDAMRINPSAEM-----VMIDRM---FNQEERASLSRDKRL---ALVDPEGFQADFCCSFKL 831

  Fly  2303 KEEIKQEPIDKSAQPDGVVDKFDLLKNSADVNKAFSKSQPQQTTTVKQEESNESGEPSV------ 2361
            .|...:.|:|:|.|                     .:|:......|.:.:|.:..:|.|
  Rat   832 DEAAPETPLDRSDQ---------------------HRSKTSSLHQVPRAQSRDRAKPGVAEATNH 875

  Fly  2362 ----------------NGSVKSEGHDKESSKYIKKDYDNFDIESELTTSFIMKKVENKAALAKSA 2410
                            |.|.|||||    |:.:|.|                          |..
  Rat   876 DQFHLVPNHIVVSAEGNISKKSEGH----SRTLKFD--------------------------KGV 910

  Fly  2411 ENRYQ---ERNMMDQQQQQQHIKANGGDPVDQDDGWYCLQKELNLMNNDHMQQSQQQLNGNQQHL 2472
            ..:|:   |    |:..::...||:|..|..:.       ....|...||         |::..|
  Rat   911 LGQYRGPPE----DKGGRRDPAKASGCSPGPEG-------HRKTLPRPDH---------GSESKL 955

  Fly  2473 P----INRQPAPQQSHFLD----NSNSNN------MMGNSNHMSDLFPNGCIDKSNQSTTSSSN- 2522
            |    .:....|....|.|    ||..|.      |.|:.....||.....::|:.::.....|
  Rat   956 PGILASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNA 1020

  Fly  2523 ---------SSCVSESLPGSNPVKTVSSC 2542
                     |..|....|..:|:.:..:|
  Rat  1021 GRPQNDPAASGAVDLDFPSFSPMASQENC 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11873	NP_001263051.1	GLTSCR1	2170..2271	CDD:291902	26/105 (25%)
Bicral	NP_001100358.1	GLTSCR1	712..812	CDD:405846	26/111 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11693
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45374
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15572
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.100