Protein Alignment CG11873 and bicra

DIOPT Version :9

• Sequence 1: NP_001263051.1
• Gene: CG11873 / 43435
• FlyBaseID: FBgn0039633
• Length: 3003
• Species: Drosophila melanogaster
• Sequence 2: XP_012823408.2
• Gene: bicra / 100135088
• XenbaseID: XB-GENE-5891820
• Length: 1766
• Species: Xenopus tropicalis
• Alignment Length: 2187
• Identity: 458/2187 - (20%)
• Similarity: 698/2187 - (31%)
• Gaps: 776/2187 - (35%)

  Fly   858 PNQNGSDGLPFTLTIPAPQPQSSTG---SQAAGNESATEI--PNILIKID----------PSAEA 907
            |:|.|.|.|.......|......||   .:|.||...||.  |...:.:|          |||.:
 Frog    26 PDQIGGDDLLDNTGDAASAFFVGTGLHVQEAPGNHLTTESNPPTASVDLDFLEDDDILGSPSAGS 90

  Fly   908 AVPPFGLSTPRLPTAEEIQKQAQQHLAQQAAAAAAAAKATTATPTINISLPSMTLQPQVAPAPVV 972
            |         .|.:|::.....||.| |:|.......:|.......:..||  ||||.|..||..
 Frog    91 A---------SLASADQPCDILQQSL-QEANITEQTLEAEAELDLGSFQLP--TLQPVVQAAPDG 143

  Fly   973 TPTPAPSSNQVSTTVVVKPRRKPAVRRNAKKPDVTSSASNMISSSSGTTTTISSSTSTILNNSQP 1037
            ||                                                .|.|..:.::...||
 Frog   144 TP------------------------------------------------QIFSGGADLIGLQQP 160

  Fly  1038 TTVNTITLTTPTPVTSSSNSTLMLTHGTPTAVPSQIGNIQISQVHNHHPSALPVSSAVENKIQIM 1102
            ..:....|...:......|..:.:   .|......:||:.|..:.|                  :
 Frog   161 AVLTHQALVQQSVGADVVNKAISV---QPFLQQVGLGNVTIQPISN------------------L 204

  Fly  1103 PILPPGATVMGGTPGTGGHAPTTQSTQLVFQPA----APSVAPT-ITSDSTGFKLSSDGRQMQLV 1162
            |.||.|:.  ||..|.|......|....:.|||    |..|.|| :.:...|..|:....:.|.|
 Frog   205 PGLPNGSP--GGALGIGQIQVVGQQVMAINQPAQQLIAKQVQPTQVANLPVGSYLAGTNTEQQQV 267

  Fly  1163 AIPQATPPSPAASSAQPPVPTPTPALTAGGATILPPQLTGM------PANVSVSVGSPASAAALV 1221
                                    .||:.|.:   ||.||:      ||..:...|:....:...
 Frog   268 ------------------------TLTSSGVS---PQNTGLVLQNKIPAVATTLNGNSMFGSVSA 305

  Fly  1222 PQLTGSLTLTVSEQCERLILRHDPNNPQDHQSQLILQALLKGALPNVTIINEPTRVDPNKQTTPM 1286
            .|.|.|||:| |.....:|::..|..         :|....|.||.......|...:||..|
 Frog   306 AQCTQSLTVT-SSLNSPVIIQRTPTP---------IQPKPAGVLPQKLFQISPKPFNPNNAT--- 357

  Fly  1287 LQPQQQVIQIPQPLTQPQQILQQQPKVSTAPKIEVKVANNRKLSGQVTHPASSMLGMTSTTTTMS 1351
                         ||...:...||||                               |.......
 Frog   358 -------------LTIQGEAALQQPK-------------------------------TQQNLAFM 378

  Fly  1352 TMKPPANLPAKQNEVVS-FPQ-LPLNSQVLIQQQPMISAQLQPQLQPVTVPVSLPTQPVPIPSPA 1414
            |.||..|:      |:| ||| ||.|   :.:|.|   :|.|...:|::  |.|..|...|..||
 Frog   379 TGKPGPNV------VLSGFPQGLPTN---MFKQPP---SQQQALGKPMS--VQLLNQGSSIVIPA 429

  Fly  1415 PAPQLANNGQQRYI---------ALPPIDPTTQQLFCLNSVTNQITAMS--AGQT--AASIGPTE 1466
            ...|....||.:::         |:.|:.....      ::..||.|.|  .||.  .||.||..
 Frog   430 QHAQAMLQGQNQFLLPGQLAGASAVQPLSALQA------NMGGQILAASHPGGQAHIIASQGPGG 488

  Fly  1467 RLL--IAPAGI-NAQQLAQCLQLGQLHFNDVNPLPAQQQQQQVATTSSSMTLSMPLRPQPPQQQI 1528
            :||  ..||.| ..|.:|..|.|||:       |.:|...      .::..||.|::.|  ..|:
 Frog   489 QLLNQALPAQILTNQNIASQLNLGQV-------LASQNAH------GTAHILSGPIQLQ--AGQV 538

  Fly  1529 VHPI---QPITNGLAITTTASSTLTTTTSTTSLT-----TVTKQVANVAPIIDQSKAKLEPAKAA 1585
            ..|.   .|::...:::|.:.:::.|:.:....|     |:..|||...|..:..:| :...:|.
 Frog   539 GQPTLFQMPVSLAGSLSTQSQASVATSLNQAGQTVIQGVTLPNQVAMFNPSENLGQA-VSIQQAP 602

  Fly  1586 TSGAGGGAVVKKKPVRK--------PKATPTNASELANLKNASVVKPMPKLD------PLSQKPN 1636
            |..:....:|:::..::        |.|...:...:...:.||..:|..:|:      .|:..|
 Frog   603 TGNSQSPGIVQQQQAQQVVQGASILPNADQPSILTVQTAQQASQGQPQLQLNVQQQTQSLAPPP- 666

  Fly  1637 NNPVQIVQ----PNVASGKQMIVVGSSSCTTTTTTTMSA-SIQPFQTTSGTKLVGVTVPMQQQQP 1696
              |.|.||    |::|:....|::|.:    |:.|.:|| |:|.|              :||:..
 Frog   667 --PQQAVQSQPSPSLATSPDKIILGGA----TSGTLLSAESMQMF--------------LQQKDQ 711

  Fly  1697 TGTAAILQQQQQQRTSFSLTATTVATPAPMP-------------------SPTV---------AS 1733
            ....|.|:.||:.    ||..|:.||..|||                   |.:|         ||
 Frog   712 QFYEAALKMQQES----SLVQTSAATHVPMPIYSLAASASTMNSSSTTTTSSSVPASVIVSSSAS 772

  Fly  1734 GVSQLQMQ------------------QLPSQQAQQ----------------------------QL 1752
            ..|||..:                  ..||.|:||                            ||
 Frog   773 SASQLNRELVQNLGTAAEPKGQSHIPHFPSSQSQQALACQIPSGQQKVPGASPSHSLPHPPSPQL 837

  Fly  1753 QP--------QQQQQLHAPKQQQP--------------QPNTVSRVQTIQL----TPQMQQIFKQ 1791
            ||        |...|...|.|.||              ||.:|.|..:..|    |||||.:| .
 Frog   838 QPSSSHLSQMQSPHQSRPPSQPQPLSRPPSRPHSRPPSQPQSVPRPPSEPLSRSCTPQMQNLF-V 901

  Fly  1792 VQMQIQFLTIKLQNKSTFLPVSPEIDSATIAAYNKPMTDAEINLALQRLFAEQHRILASGKEVPT 1856
            :|.||               .||...|                         ||.:    :....
 Frog   902 IQNQI---------------ASPHGSS-------------------------QHPL----RPPSQ 922

  Fly  1857 PEGMLPTANGTGGFSLMPQPVQQQQQQQQQQLQSTVPE-------PLKTIVPANVVQPNNHS--- 1911
            |:...|.|:...  |.:||.:...||..|.|:|.:.|:       |:.....|:...|..||
 Frog   923 PQVQTPFASHQP--SDIPQTLSSPQQHIQLQVQLSTPQSEIRAGVPVSLQATASSSDPQTHSFQL 985

  Fly  1912 ----STPAGAATSGATTAANIQQNITQRIHIYPMQHQQQQQ---QQQQQQQQQPQHQQQQPQHQL 1969
                .||...:.|..|....:... |:....:.|.|.|.|.   |....||:|...:.||.| ||
 Frog   986 QFQAQTPIKTSISPQTAGQPLHLT-TESQRTFQMTHSQIQALSLQNSVPQQKQLLERYQQMQ-QL 1048

  Fly  1970 QQTGAKPKQAQPKPPPQQEQQSQLQIKPKEPANRSKVTSQQLQQNPQPPNGTINMLPQKVSMMPV 2034
            ||....|.|.|                         :||.|    ..|..|     .|.....|.
 Frog  1049 QQGLMLPSQQQ-------------------------ITSTQ----TSPALG-----GQYSGQAPS 1079

  Fly  2035 VQQQQQQQPQQHQQQPMLNKSGPPPLIFASSTNMLSNSNSNNLHNSNSAMQVNNMLPLPPLQPQQ 2099
            |....|.||.. .|.|:|..|  |..:....|..||..   .:..||.|.|::.:|       ||
 Frog  1080 VLTSGQGQPVL-SQGPLLGHS--PGQVLVQPTPDLSKV---QVGGSNQAAQLSTLL-------QQ 1131

  Fly  2100 QPQPQLQQPPTP------------ILPPVAPTMAMGVAPGPMGNLV-PSLPTIPSLPLYMPSK-- 2149
            |....|.:...|            .:||     .:.|.|.|:|..| ....::.:||:..|.|
 Frog  1132 QQATVLVKSSAPSYCLLSAGSAAATVPP-----DVNVYPSPVGKSVGGQCKSVAALPVQTPGKTA 1191

  Fly  2150 ---------------------------------------------MDEMPTQKPKIARLSLFVRQ 2169
                                                         :.::||.:|  ::.:.|:..
 Frog  1192 VISSVSGLSLGKGSVQIQVVGKGMPQIVSTAQTPAQPQFESKFGALKKLPTLQP--SKEACFLEH 1254

  Fly  2170 LEVDQESCLKPDYVKPFRTKDEAVKRLIRYHCMHENDVELPSD---EDEEFESTALEFQDKFRQL 2231
            |...|.|.|.|||..||.:.::|..||:.|| :::..:....|   .|||||..:.:...:.:.:
 Frog  1255 LHKHQGSVLHPDYKSPFHSFEDAFHRLLPYH-VYQGLLPTTHDLRKVDEEFEVVSTQLLKRTQAM 1318

  Fly  2232 NGKFQEILMQESTLPHRTSELLQMQQLMIDDLKGEINEIRTAEKELEQQLKEEQTSEKSTAESDV 2296
            ..|::.:|::||.....::|::.:.::.|.:.|..::        |::||.:|:..|..::
 Frog  1319 LNKYRLLLLEESKRVSPSAEMVMIDRMFIQEEKVALS--------LDRQLAKERPDEYVSS---- 1371

  Fly  2297 LSEAKVKEEIKQEP-IDKSAQPDGVVDKFDLLKNSADVNKAFSKSQPQQTTTVKQEESNESGEPS 2360
             |.::.:..:...| :..|..|   |...::||.:     ....|.|...|.:..:.|. .|.||
 Frog  1372 -SSSRSQTFVPMAPSVSSSPCP---VPAPEILKPT-----VVQTSTPIHPTKLVIKHSG-GGSPS 1426

  Fly  2361 VNGSVKSEGHDKESS---KYIKKDYDNFDIESELTTSFIMKKVENKAALAKSAENRYQERNMMDQ 2422
            |..:..|...|.:..   ...|.....::..|.:.   :..|::.:|.|:|...|
 Frog  1427 VTWAKASPSLDTDDDALPSRSKPPIKTYEARSRIG---LKLKIKQEAGLSKVIHN---------- 1478

  Fly  2423 QQQQQHIKANGGDPVDQDD------------GWYCLQKELNLMNNDHMQQSQQQLNGNQQH-LPI 2474
                     ...|||.|:.            ....:.|.........:.....|:||..:| ||.
 Frog  1479 ---------TALDPVHQNPPPPPPPPAPPTVPTSTVIKAAVQSTPATITTPTGQMNGTLEHSLPA 1534

  Fly  2475 NRQP------APQQSHFLDNSNSNNMMGNSNHMSDLFPNGCIDKSNQSTTSSSNSSCVSESLPGS 2533
            .::|      .|.:..:.:|             .|.|..|
 Frog  1535 EKKPLATYCRLPLRKTYREN-------------VDAFVTG------------------------- 1561

  Fly  2534 NPVKTVSSCSGQREQPVVMDADQQNE--HPAISEFFSSDSDVQKSVETRLEAMFG---------- 2586
            .|...:|......:.|.||...:|.:  ...|:...:..|...:.|:....|..|
 Frog  1562 KPADVLSKMDKPAQPPTVMHQVKQEDGSRSVITSHKTQGSSHTEKVKKEENAKLGIYHRVEPKTN 1626

  Fly  2587 ---ESPVHL--DVKSSNDA-------NDIESNLDEIFGDSKSPAANHKSKMSMWVPDASFMQQAP 2639
               |:||.|  |||..:.:       .:...|..|:..:.:.|:|.........|.:|||...:|
 Frog  1627 NSDENPVGLRHDVKDDDQSYYRKIIKTEPPDNEAELNWEMQLPSAKRLKSEPFDVDNASFSSDSP 1691

  Fly  2640 QQQTSQQQQQYA-----GPQQPSQQQHHIELNCNNNPRWMQSMEAHYSDFLSTGTSNGELVNGES 2699
            |..|..:..|.|     ..|||..
 Frog  1692 QDDTLNEHLQSAIDSILNLQQPQS----------------------------------------- 1715

  Fly  2700 RKRSWDSQLMGSGSDMEDDNSSKRLCTASS---SSSSSPMSS 2738
                      |.|:     ||..|..|.||   ||||||.||
 Frog  1716 ----------GGGT-----NSLLRSSTQSSYHHSSSSSPFSS 1742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11873	NP_001263051.1	GLTSCR1	2170..2271	CDD:291902	27/103 (26%)
bicra	XP_012823408.2	Med15	337..>683	CDD:312941	98/431 (23%)
		Atrophin-1	802..>1009	CDD:397323	54/253 (21%)
		GLTSCR1	1258..1359	CDD:405846	27/109 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12012
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto103643
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050