DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul5 and AT1G59790

DIOPT Version :9

Sequence 1:	NP_651665.2	Gene:	Cul5 / 43434	FlyBaseID:	FBgn0039632	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_176188.1	Gene:	AT1G59790 / 842272	AraportID:	AT1G59790	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	91/468 - (19%)
Similarity:	164/468 - (35%)	Gaps:	146/468 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RDRDI-FEEVWPDKRRIVLKLLR------QDTVSQREWQDLFFGVHFVCLWDEKGAAKIYDCLQQ 65
            |.|.| |||.|.:.::.:.||:|      :.|....|...|:..::.:|:.....:.::|:..::
plant     8 RPRQIKFEEGWSNIQKGITKLIRILEGEPEPTFYFSECFKLYTIIYDMCVQRSDYSQQLYEKYRK 72

  Fly    66 DIVEFIVQAQSQVQAQRGEQALLATYIVEWR----------KFF-------TQSNYLPLPFRQLE 113
            .|.::.:|.......::.::.:|...:..|.          |||       .:.:.:|:|  .|:
plant    73 VIEDYTIQTVLPSLREKHDEDMLRELVKRWNNHKIMVKWLSKFFVYIDRHLVRRSKIPIP--SLD 135

  Fly   114 QSPQVKPSSSGSSSSASVSASGASTSAAAAAAATSCSGQAGKSGASTSAAAGASTSAAAAAASTS 178
            :                              ...:|
plant   136 E------------------------------VGLTC----------------------------- 141

  Fly   179 ASTSSAAAAAAASGSGSSSSSTSTSKKNPTEDSPVRKLMLDSWNKHIFHDIKHRLQESAMKIVHA 243
                                                  .||.    ::.:::...:|..:.::|.
plant   142 --------------------------------------FLDL----VYCEMQSTAKEVVIALIHK 164

  Fly   244 ERNGDAYDAQLVVGVRESYVNLSSNAEDKLEIYRENFEMAYLKATVEFYRLKSAEQQQENGVLAY 308
            ||.|:..|..||..|.:.||   .|....||.|.|:||...|:.|..:|..|::...:|:....|
plant   165 EREGEQIDRALVKNVLDIYV---ENGMGTLEKYEEDFESFMLQDTASYYSRKASRWTEEDSCPDY 226

  Fly   309 MKYADSKLREEEVRAKRYLEPSSFSILTYTLVNVLIV----DHLNSIIAECPALIRDYETERLNL 369
            |...:..|:.|..|...||...:...|...:.|.|:|    :.|.:..:...||:||.:...|:.
plant   227 MIKVEECLKMERERVTHYLHSITEPKLVEKIQNELLVMVTKNRLENEHSGFSALLRDDKKNDLSR 291

  Fly   370 MFRLMDRVMHGVGVEPMMGDL-QRHIMSAGLADMLSASEVITQDSEKYVERLL-ELFNKFSDLVR 432
            ::||...:...:|   .:.|| ::||...|.|       :|.|..:|...:|| ||.|||...|.
plant   292 IYRLYLPIPKRLG---RVADLFKKHITEEGNA-------LIKQADDKTTNQLLIELHNKFIVYVI 346

  Fly   433 NAFNDDPRFLTAR 445
            ..|.:...|...|
plant   347 ECFQNHTLFHKVR 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul5	NP_651665.2	Cullin	33..743	CDD:279260	80/436 (18%)
		CULLIN	520..655	CDD:214545
		Cullin_Nedd8	779..846	CDD:214883
AT1G59790	NP_176188.1	Cullin	47..>357	CDD:279260	78/425 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820