Protein Alignment Sirt7 and HST1

DIOPT Version :9

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_014573.1
• Gene: HST1 / 854086
• SGDID: S000005429
• Length: 503
• Species: Saccharomyces cerevisiae
• Alignment Length: 412
• Identity: 81/412 - (19%)
• Similarity: 148/412 - (35%)
• Gaps: 107/412 - (25%)

  Fly     1 MEKDLG---EEKDQDQEQNTEMEPKQEMDVAQSYITRAKMNPAKKDNEKRRRKDAMRRVSMILRK 62
            |.|.||   ::|:.....|:.:...:|...|:.....||.....:..:...:|.|::.:
Yeast   109 MIKLLGFDVKDKELFMALNSNITSNKERSSAELSSIHAKAEDEDELTDPLEKKHAVKLI------ 167

  Fly    63 CDSMRTTEDRQFLEKHPDMVKTTKKRKERVEIYKERVVEREDAPHVIEAKVEQLANIISQAKHLV 127
                      :.|:|..:.|.:|:.|.....                  .::.....:..||.::
Yeast   168 ----------KDLQKAINKVLSTRLRLPNFN------------------TIDHFTATLRNAKKIL 204

  Fly   128 CYTGAGISTAALIPDYRGSQGIWTL-----LQKGQDIGEHDLSSANPT----YTHMALYELHRRR 183
            ..||||:||:..|||:|.|:|.::.     |:..||:...|:...:|:    ..||.|...:...
Yeast   205 VLTGAGVSTSLGIPDFRSSEGFYSKIRHLGLEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYS 269

  Fly   184 LLHHVV-------------SQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCR---PNSVYWRQF 232
            .||..:             :||.|.|...:|:..:.|.:.||:.....|..|.   |....:...
Yeast   270 PLHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENI 334

  Fly   233 DTTEM-TARYCHKTHRLCHRCS--EPLYDTIVHFG-----ERGNVKWPLNWAGATANAQ------ 283
            ...|: ...||::..:.....|  .....|.::|.     ..|.:|..:.:.|....::
Yeast   335 RNLELPLCPYCYQKRKQYFPMSNGNNTVQTNINFNSPILKSYGVLKPDMTFFGEALPSRFHKTIR 399

  Fly   284 ----RADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNL--QWTPKDAI-------ASIKI 335
                ..|:::|:|:||||           .|..:     :||:  ...|:..|       |...:
Yeast   400 KDILECDLLICIGTSLKV-----------APVSE-----IVNMVPSHVPQILINRDMVTHAEFDL 448

  Fly   336 N--GKCDQVMAQLMHLLHIPVP 355
            |  |.||.|.:.:....|..:|
Yeast   449 NLLGFCDDVASLVAKKCHWDIP 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	57/267 (21%)
HST1	NP_014573.1	DUF592	53..207	CDD:368003	19/131 (15%)
		SIRT1	201..461	CDD:238699	61/275 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810