Protein Alignment Sirt7 and sirt4

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001005988.1
• Gene: sirt4 / 791628
• ZFINID: ZDB-GENE-041010-65
• Length: 310
• Species: Danio rerio
• Alignment Length: 277
• Identity: 77/277 - (27%)
• Similarity: 124/277 - (44%)
• Gaps: 58/277 - (20%)

  Fly   113 VEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGI---------------WTLLQKGQD---- 158
            :|||...||||..|...:|||:||.:.||||| |:|:               :...:|.:.
Zfish    40 LEQLQAFISQASRLFVISGAGLSTESGIPDYR-SEGVGLYARTNRRPMQHSEFVRSEKSRQRYWA 103

  Fly   159 ---IGEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCK 220
               :|....||..|...|:||.:...:..||.:|:||.|.|||::|..|  |:|:||:.:..||.
Zfish   104 RNYVGWPQFSSHQPNSAHLALRDWEEKGKLHWLVTQNVDALHLKAGQQR--LTELHGSTHRVVCL 166

  Fly   221 NC---RPNSVYWRQFDTT----EMTA--------RYCHKTHRL------CHRCSEPLYDTIVHFG 264
            :|   .|.:...::|...    |.||        .:..:...|      |:.|...|...:..||
Zfish   167 DCGELTPRAELQKRFTALNPGWEATACAVAPDGDVFLEEEQVLNFRVPACNACGGVLKPEVTFFG 231

  Fly   265 E---RGNVKWPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTP 326
            :   |..|.:..|      ....:|.:|..||||:|...|.:|.   ..:.::..|.:||:..|.
Zfish   232 DVVNRNTVHFVHN------KLAESDAVLVAGSSLQVFSGYRFLL---AASERKLPIAIVNIGATR 287

  Fly   327 KDAIASIKINGKCDQVM 343
            .|.:..|:::.:|.:|:
Zfish   288 ADHLTDIRVSARCGEVL 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	68/259 (26%)
sirt4	NP_001005988.1	SIRT4	43..304	CDD:238700	74/272 (27%)