DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sirt7 and sirt4

DIOPT Version :9

Sequence 1:NP_651664.2 Gene:Sirt7 / 43433 FlyBaseID:FBgn0039631 Length:771 Species:Drosophila melanogaster
Sequence 2:NP_001039093.1 Gene:sirt4 / 733911 XenbaseID:XB-GENE-948981 Length:322 Species:Xenopus tropicalis


Alignment Length:299 Identity:80/299 - (26%)
Similarity:127/299 - (42%) Gaps:84/299 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 PHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGI--------------------- 149
            ||    :||||.:.:||::.|...|||||||.:.||||| |:|:                     
 Frog    40 PH----QVEQLQDFVSQSQRLFVMTGAGISTESGIPDYR-SEGVGLYSRTERRPIQHSEFVQSQA 99

  Fly   150 -----WTLLQKGQDIGEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSE 209
                 |.    ...:|....||..|...|:.|.:..|...||.:|:||.|.||.::|..|  |||
 Frog   100 ARRRYWA----RNFVGWPSFSSHEPNSAHVNLCKWERAGRLHWLVTQNVDALHTKAGQCR--LSE 158

  Fly   210 IHGNMYVEVCKNCRPNSVYWRQFDTTEMTARYCH-------KTHRL------------------- 248
            :||..:..:|..|:  :|..|    :|:..|:.:       :.|.|                   
 Frog   159 LHGCTHRVICLGCQ--TVTKR----SELQERFLNLNPSWNEQAHGLAPDGDVFLTDEQVSDFQVP 217

  Fly   249 -CHRCSEPLYDTIVHFGE---RGNVKWPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDR 309
             |.:|...|...:..||:   ||.|      .......::||.:|.:||||:|...|.:...   
 Frog   218 ACTKCGGILKPQVTFFGDTVNRGFV------FSIYEQMKQADAMLIVGSSLQVYSGYRFALN--- 273

  Fly   310 PARQ-RAKICVVNLQWTPKDAIASIKINGKCDQVMAQLM 347
             |:: ...|.::|:..|..|.:|.:|::.:|..|:..::
 Frog   274 -AKELHLPIAILNIGPTRADHLAKVKVSARCGDVLPHIL 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sirt7NP_651664.2 SIRT7 124..338 CDD:238701 70/270 (26%)
sirt4NP_001039093.1 SIRT4 46..307 CDD:238700 74/283 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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