Protein Alignment Sirt7 and sirt3

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: XP_009301762.1
• Gene: sirt3 / 558775
• ZFINID: ZDB-GENE-070112-1762
• Length: 358
• Species: Danio rerio
• Alignment Length: 216
• Identity: 60/216 - (27%)
• Similarity: 92/216 - (42%)
• Gaps: 35/216 - (16%)

  Fly   107 HVIEAKVEQLANIISQA--KHLVCYTGAGISTAALIPDYRG-SQGIWTLLQK-----GQDIGE-- 161
            :|.:..:|.:|..|.:.  |.:|...||||||.:.|||:|. ..|::..||:     .:.|.|
Zfish    82 NVHQQTLEDIAEKIRERKFKRIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYNLPYAEAIFEIN 146

  Fly   162 -------------HDLSSAN--PTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIH 211
                         .:|...|  |..||..:..||.:..|..:.:||.|||...:|:|...|.|.|
Zfish   147 YFHHNPNPFFALAKELYPGNYQPNLTHYFIRMLHDKEQLLRMYTQNIDGLERMAGIPPKMLVEAH 211

  Fly   212 GNMYVEVCKNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLNWA 276
            |......|..||      |.:...|:.......|...|..|...:...||.|||    :.|.::.
Zfish   212 GTFATATCTVCR------RDYKGEELRDDIMAGTVPKCPTCKGIIKPDIVFFGE----ELPQHFF 266

  Fly   277 GATANAQRADVILCLGSSLKV 297
            ....:...||:::.:|:||:|
Zfish   267 TYLTDFPIADLLIVMGTSLEV 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	56/197 (28%)
sirt3	XP_009301762.1	SIRT1	101..337	CDD:238699	56/197 (28%)