Protein Alignment Sirt7 and SIRT7

DIOPT Version :9

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: XP_024306560.1
• Gene: SIRT7 / 51547
• HGNCID: 14935
• Length: 442
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 186/408 - (45%)
• Similarity: 247/408 - (60%)
• Gaps: 44/408 - (10%)

  Fly    27 VAQSYITRAKMNPAKKDNEKR--RRKDAMRRVSMILRKCDSMRTTEDRQFLEKHPDMVKTTKKRK 89
            :|...::|::...|::....|  ::::.:|:||.||||..:.|:.|:.:.|.:..|:|...:.|.
Human     1 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRS 65

  Fly    90 ERVEIYKERVVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQ 154
            .|.|..|.|..|..|.|..:..||.:||:.:..||:||.||||||||||.||||||..|:|||||
Human    66 RRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQ 130

  Fly   155 KGQDIGEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVC 219
            ||:.:...|||.|.||.|||::..||.::|:.||||||||||||||||||.::||:|||||:|||
Human   131 KGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVC 195

  Fly   220 KNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLNWAGATANAQR 284
            .:|.||..|.|.||.||.||.:.|:|.|.||:|...|.||||||||||.:..||||..||..|.|
Human   196 TSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASR 260

  Fly   285 ADVILCLGSSLK------------------------------------------VLKKYTWLWQM 307
            ||.|||||||||                                          |||||..||.|
Human   261 ADTILCLGSSLKVRADDTMSEPSPCPPEGVQLCGPALYRLVPCVCAVSVCLLPQVLKKYPRLWCM 325

  Fly   308 DRPARQRAKICVVNLQWTPKDAIASIKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLM 372
            .:|..:|.|:.:|||||||||..|::|::||||.||..||..|.:.:|.|::.:||||:.|:.|.
Human   326 TKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLR 390

  Fly   373 PEELHTLTQPLLKNADEE 390
            ..|..:.::..|..:.||
Human   391 AGEEGSHSRKSLCRSREE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	136/255 (53%)
SIRT7	XP_024306560.1	YscO	16..>101	CDD:284686	26/84 (31%)
		SIRT7	100..356	CDD:238701	136/255 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158964
Domainoid	1	1.000	186	1.000	Domainoid score	I3366
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56152
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D468902at33208
OrthoFinder	1	1.000	-	-		FOG0008203
OrthoInspector	1	1.000	-	-		oto91462
orthoMCL	1	0.900	-	-		OOG6_107533
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6170
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.710