Protein Alignment Sirt7 and Sirt2

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_650880.3
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Alignment Length: 356
• Identity: 83/356 - (23%)
• Similarity: 147/356 - (41%)
• Gaps: 83/356 - (23%)

  Fly   110 EAKVEQLANIIS---QAKH--------LVCYTGAGISTAALIPDYRG-SQGIWTLLQKGQ----- 157
            |.|||::...:|   .|:|        :|...||||||:|.|||:|. ..|:::.|:|.:
  Fly    54 EVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPT 118

  Fly   158 ---DIGEHDLSSAN--------------PTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRN 205
               |:...:.:.|.              ||..|..:..|:.:.||....:||.|.|...:|||.:
  Fly   119 AIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPED 183

  Fly   206 SLSEIHGNMYVEVCKNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVK 270
            .:.|.||:.:...|..||      :::|...|.|.........|.:|...:...||.|||....:
  Fly   184 KIIEAHGSFHTNHCIKCR------KEYDMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGENLPKR 242

  Fly   271 WPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQ---------MDRPARQRAKICVV------ 320
            :   ::....:.|..|:::.:|:||:|....:.:|:         ::|.|..:|. ||:
  Fly   243 F---YSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQAS-CVLFMDPNT 303

  Fly   321 -NLQWTPKDAIASIKINGKCDQ-VMA---------QLMHLLHIPVPVYTKEKDPIFAHASLLMPE 374
             :|.:...:....:...|.||. |||         :|..|:       |.|:..:....:   .|
  Fly   304 RSLLFDKPNNTRDVAFLGDCDAGVMALAKALGWDQELQQLI-------TSERKKLSGSQN---SE 358

  Fly   375 ELHTLTQPLLKNADEEEAFTTTTEETQDSTI 405
            ||.   |...|...:.:..|:...:.:|:::
  Fly   359 ELQ---QGKEKPQSDPDKMTSGDRDKKDASL 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	60/260 (23%)
Sirt2	NP_650880.3	SIRT1	79..330	CDD:238699	64/260 (25%)