Protein Alignment Sirt7 and Sirt4

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 92/344 - (26%)
• Similarity: 139/344 - (40%)
• Gaps: 95/344 - (27%)

  Fly    55 RVSMILR-KCDSMRTTEDRQFLEKHPDMVKTTKKRKERVEIYKERVVEREDAPH---VIEAKVEQ 115
            ||..:|| :..|:|::..||                             |..||   |:|..:::
  Fly     2 RVGQLLRFRSTSLRSSTARQ-----------------------------EYVPHHKPVVEDDIKR 37

  Fly   116 LANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQD---------------------- 158
            |.:.:....:::..|||||||.:.||||| |:|:....:....
  Fly    38 LEDFLLSKPNVLVLTGAGISTESGIPDYR-SEGVGLYARSNHKPVQHMEFVKSSAVRKRYWARNF 101

  Fly   159 IGEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCR 223
            :|....|:..|..||.||....|...:..||:||.|.||.::| .|| :.|:||:.||..|.:|.
  Fly   102 VGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG-SRN-VVEVHGSGYVVKCLSCE 164

  Fly   224 ----------------------PNSVYWRQFDTTEMTARYCHKTHRL--CHRCSEPLYDTIVHFG 264
                                  |:.:  |.....|:...|. :..|:  |.:|...|...||.||
  Fly   165 YRIDRHEFQSILASLNPAFKDAPDMI--RPDGDVEIPLEYI-ENFRIPECTQCGGDLKPEIVFFG 226

  Fly   265 ERGNVKWPL--NWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPK 327
            :  :|..|.  ..||...|   :|.:|.|||||.|...|..:.|   ....:..:.:||:..|..
  Fly   227 D--SVPRPRVDQIAGMVYN---SDGLLVLGSSLLVFSGYRVVLQ---TKDLKLPVGIVNIGETRA 283

  Fly   328 DAIASIKINGKCDQVMAQL 346
            |.:|.|||:.||..|:.:|
  Fly   284 DHLADIKISAKCGDVIPKL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	74/261 (28%)
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	77/274 (28%)