Protein Alignment Sirt7 and Sirt5

DIOPT Version :9

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001004256.1
• Gene: Sirt5 / 306840
• RGDID: 1303285
• Length: 310
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 62/270 - (22%)
• Similarity: 105/270 - (38%)
• Gaps: 59/270 - (21%)

  Fly   121 SQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQDIGEHDLSSANPTYT------------- 172
            :.|||:|..:|||:|..:.:|.:||:.|.|...| .|.:......:.||:..
  Rat    48 ANAKHIVIISGAGVSAESGVPTFRGTGGYWRKWQ-AQHLATPLAFAHNPSQVWEFYHYRREVMRN 111

  Fly   173 ------HMALYELHR------RRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCRPN 225
                  |:|:.:...      ||::  |::||.|.||.::|  ..:|.||||.::...|.:|...
  Rat   112 KEPNPGHLAIAQCEARLRDQGRRVV--VITQNIDELHRKAG--TKNLLEIHGTLFKTRCTSCGNV 172

  Fly   226 SVYWR-------------QFDTTEMTARYCHKTHRLCHRCSEP-----LYDTIVHFGERGNVKWP 272
            :..::             :.||.|...    ..|:| .||.|.     |...:|.|||..:   |
  Rat   173 AENYKSPICPALLGKGAPEPDTQESRI----PVHKL-PRCEEAGCGGLLRPHVVWFGENLD---P 229

  Fly   273 LNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIASIKING 337
            ...........|.|:.|.:|:|..|.....:..|:   |.:...:...|::.||..........|
  Rat   230 AILKEVDRELARCDLCLVVGTSSVVYPAAMFAPQV---ASRGVPVAEFNMETTPATNRFRFHFPG 291

  Fly   338 KCDQVMAQLM 347
            .|...:.:.:
  Rat   292 PCGVTLPEAL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	59/256 (23%)
Sirt5	NP_001004256.1	SIRT5_Af1_CobB	51..301	CDD:238703	61/265 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810