Protein Alignment Sirt7 and Sirt6

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: XP_063119252.1
• Gene: Sirt6 / 299638
• RGDID: 1305216
• Length: 357
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 112/390 - (28%)
• Similarity: 170/390 - (43%)
• Gaps: 118/390 - (30%)

  Fly   104 DAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQ----DIGEHDL 164
            |.|..:|.||.:||.::.|:..:|.:||||||||:.|||:||..|:||:.::|.    ||   ..
  Rat    25 DPPEELECKVWELARLMWQSSTVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDI---TF 86

  Fly   165 SSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCRPNSVYW 229
            .:|.|:.|||||.:|.|...|..:||||.||||:|||.||:.|:|:||||:||.|..|:...|..
  Rat    87 ENARPSKTHMALVQLERMGFLSFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECPKCKTQYVRD 151

  Fly   230 RQFDTTEMTARYCHKTHRLC--------HRCSEPLYDTIVHFGERGNVKWPLNWAGATAN----- 281
            ....|..:.|     |.|||        ..|...|.|||            |:|..|..:
  Rat   152 TVVGTMGLKA-----TGRLCTVAKARGLRACRGELRDTI------------LDWEDALPDRDLTL 199

  Fly   282 ----AQRADVILCLGSSLKVLKKYTWLWQMDRPA--------RQRAKICVVNLQWTP-------- 326
                ::.||:.:.||:||::           ||:        |:..::.:||||.|.
  Rat   200 ADEASRTADLSVTLGTSLQI-----------RPSGNLPLATKRRGGRLVIVNLQPTKHVCASALP 253

  Fly   327 -------------------KDAIASIKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLM 372
                               :|..|.:.|:|..|:||.:||..|.:.:|.:...:         ::
  Rat   254 SAPVSPACPLRRTDCPSLWQDRQADLCIHGYVDEVMCKLMKHLGLEIPTWDGPR---------VL 309

  Fly   373 PEELHTLTQPLLKNADEEEAFTTTTEETQDSTISSESCSFNYSDLPIGKGPRIRTPIKNGRRVKT 437
            .:.|..|.:|:...|:.......:.:...||.:                      |.:..:||||
  Rat   310 EKALPPLPRPVAPKAEPPVHLNGSYKPKPDSPV----------------------PHRPPKRVKT 352

  Fly   438  437
              Rat   353  352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	85/269 (32%)
Sirt6	XP_063119252.1	None