Protein Alignment Sirt7 and hst4

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_593659.1
• Gene: hst4 / 2542366
• PomBaseID: SPAC1783.04C
• Length: 415
• Species: Schizosaccharomyces pombe
• Alignment Length: 476
• Identity: 98/476 - (20%)
• Similarity: 161/476 - (33%)
• Gaps: 163/476 - (34%)

  Fly    61 RKCDSMRTTEDR-QFLEKHPDMVKTTKKRKERVEIYKERVVEREDAPHVIEAKVEQLANIISQAK 124
            |||.|......| |.|.|.|..:.|   ..|.|::                   ..|.:.|.:||
pombe    16 RKCQSSENASKRQQLLSKLPLRLHT---GNENVDL-------------------SPLVSAIRKAK 58

  Fly   125 HLVCYTGAGISTAALIPDYRGSQGIWTLLQ-------KGQDIGE----HDLSSAN---------- 168
            .:|..||||||..|.|||:|.|:|:::.|:       .|:::.:    .||.|.|
pombe    59 RIVVVTGAGISCDAGIPDFRSSEGLFSSLRAEYKLNCSGKELFDGSVYRDLKSVNIFHAMIRKLH 123

  Fly   169 -------PTYTHMALYELHRRRLLHHVVSQNCDGLHLR-SGL----------PRNSLSEIHGNMY 215
                   ||..|:.|.:|.:...|..:.:||.|.|..| .||          |..:...:||.:.
pombe   124 MLSNNARPTDFHLFLSQLAQESKLLRLYTQNIDFLETRLEGLQTCIPLPQSAPWPTTIPLHGTLE 188

  Fly   216 VEVCKNCRPNSVYWRQFD---------------TTEMTARYCHKTHRLCHRCSEP---LYDTIVH 262
            |..|..|.    :.::|:               .||...|.......:...|..|   ||:.|..
pombe   189 VVSCTRCS----FLKKFNPDIFDRNGVTVCPDCKTENEVRRIAGKRSVIEGCLRPRIVLYNEIHP 249

  Fly   263 FGERGNVKWPLNWAGATAN---AQRADVILCLGSSLK------VLKKYT-----------WLWQM 307
            ..|.         .|:..:   ..|.|.::..|:|.|      ::|:.:           || ..
pombe   250 DSES---------IGSVCSQDLKSRPDCLIVAGTSCKIPGVKRIIKEMSNCVHKQKGNVIWL-NY 304

  Fly   308 DRPARQRAKICVVNLQWTPKDAIASIKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLM 372
            |.|.:....:|             .:.:.|.....:.:|..||..|   ..|.|.
pombe   305 DEPTKDFLNLC-------------DLVVQGDLQIAIRRLKPLLDAP---SWKLKS---------- 343

  Fly   373 PEELHTLTQPLLKNADEEEAFTTTTEETQDSTISSESCSFNYSDLPIGKGPRIRTPIKNGRRVKT 437
                |:..:...:.:.|:...|::|:.|:...::::|...:..|                   .|
pombe   344 ----HSAKRTSKQKSSEQTKITSSTKITKAIGLNTKSNDSSKKD-------------------NT 385

  Fly   438 NLELRQKFKTLNGQDEEIKVE 458
            :.:|.|...::.....|||.|
pombe   386 SFQLHQVLNSIEIPKVEIKQE 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	62/290 (21%)
hst4	NP_593659.1	SIR2-fam	58..322	CDD:238698	62/290 (21%)