Protein Alignment Sirt7 and SIRT3

DIOPT Version :9

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001357239.1
• Gene: SIRT3 / 23410
• HGNCID: 14931
• Length: 417
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 72/281 - (25%)
• Similarity: 110/281 - (39%)
• Gaps: 70/281 - (24%)

  Fly   103 EDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRG-SQGIWTLLQKGQDIGEHDL-- 164
            :|...:|.|:.         .:.:|...||||||.:.|||:|. ..|:::.||      ::||
Human   126 QDVAELIRARA---------CQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQ------QYDLPY 175

  Fly   165 --------------------------SSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLP 203
                                      .:..|..||..|..||.:.||..:.:||.|||...||:|
Human   176 PEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP 240

  Fly   204 RNSLSEIHGNMYVEVCKNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGN 268
            .:.|.|.||......|..|:      |.|...::.|.........|..|:..:...||.|||
Human   241 ASKLVEAHGTFASATCTVCQ------RPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGE--- 296

  Fly   269 VKWPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKI---CVVNLQWTPKDAI 330
             ..|..:.....:...||::|.||:||:| :.:..|.:..|.:..|..|   .|..|.|.|:
Human   297 -PLPQRFLLHVVDFPMADLLLILGTSLEV-EPFASLTEAVRSSVPRLLINRDLVGPLAWHPR--- 356

  Fly   331 ASIKINGKCDQVMAQLMHLLH 351
                     .:.:|||..::|
Human   357 ---------SRDVAQLGDVVH 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	65/245 (27%)
SIRT3	NP_001357239.1	SIRT1	138..373	CDD:238699	69/260 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810