Protein Alignment Sirt7 and Sirt7

DIOPT Version :9

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_694696.2
• Gene: Sirt7 / 209011
• MGIID: 2385849
• Length: 402
• Species: Mus musculus
• Alignment Length: 361
• Identity: 185/361 - (51%)
• Similarity: 244/361 - (67%)
• Gaps: 2/361 - (0%)

  Fly    32 ITRAKMNPAKKDNEKR--RRKDAMRRVSMILRKCDSMRTTEDRQFLEKHPDMVKTTKKRKERVEI 94
            ::|::...|::....|  ::::.:|:||.||||..:.|:.|:.:.|.:..|:|...:.|..|.|.
Mouse     7 LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESEDLVTELQGRSRRREG 71

  Fly    95 YKERVVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQDI 159
            .|.|..|..|.|..:..||.:||..:..|:|||.||||||||||.||||||..|:|||||||:.:
Mouse    72 LKRRQEEVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRPV 136

  Fly   160 GEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCRP 224
            ...|||.|.||.|||::..||.::|:.||||||||||||||||||.::||:|||||:|||.:|.|
Mouse   137 SAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCIP 201

  Fly   225 NSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLNWAGATANAQRADVIL 289
            |..|.|.||.||.||.:.|.|.|.||:|...|.||||||||||.:..||||..||..|.:||.||
Mouse   202 NREYVRVFDVTERTALHRHLTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASKADTIL 266

  Fly   290 CLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIASIKINGKCDQVMAQLMHLLHIPV 354
            ||||||||||||..||.|.:|..:|.|:.:|||||||||..|::|::||||.||..||:.|.:.:
Mouse   267 CLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMQLLMNELGLEI 331

  Fly   355 PVYTKEKDPIFAHASLLMPEELHTLTQPLLKNADEE 390
            |||.:.:||||:.|:.|...|..:.::..|..:.||
Mouse   332 PVYNRWQDPIFSLATPLRAGEEGSHSRKSLCRSREE 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	135/213 (63%)
Sirt7	NP_694696.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		3/17 (18%)
		SIRT7	102..315	CDD:238701	135/212 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..402		3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849344
Domainoid	1	1.000	183	1.000	Domainoid score	I3438
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56152
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D468902at33208
OrthoFinder	1	1.000	-	-		FOG0008203
OrthoInspector	1	1.000	-	-		oto95046
orthoMCL	1	0.900	-	-		OOG6_107533
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8274
SonicParanoid	1	1.000	-	-		X6170
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.740