DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sirt7 and LOC1273019

DIOPT Version :10

Sequence 1:NP_651664.2 Gene:Sirt7 / 43433 FlyBaseID:FBgn0039631 Length:771 Species:Drosophila melanogaster
Sequence 2:XP_311957.5 Gene:LOC1273019 / 1273019 VectorBaseID:AGAMI1_003031 Length:615 Species:Anopheles gambiae


Alignment Length:391 Identity:83/391 - (21%)
Similarity:131/391 - (33%) Gaps:157/391 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 KERVVEREDAPHVIEAKVEQLANIISQAKH--------LVCYTGAGISTAALIPDYRG-SQGIWT 151
            :.||:|..|...|:              ||        :|...||||||:|.|||:|. :.|::.
Mosquito   152 RRRVLETVDIDGVL--------------KHWKSGGFKKIVTMVGAGISTSAGIPDFRSPNTGLYN 202

  Fly   152 LLQK-----GQDIGEHDLSSAN-----------------PTYTHMALYELHRRRLLHHVVSQNCD 194
            .|.|     .|.|.|.:....|                 ||.:|..:..|.::.||....:||.|
Mosquito   203 NLMKYNLPYPQAIFELEYLHQNPKPFFTLAKELYPGTFKPTPSHYFVRLLEQKGLLVRHYTQNID 267

  Fly   195 GLHLRSGLPRNSLSEIHGNMYVEVCKNCRPNSVYWRQFDTTEMTA---RYCHKTHRLCHRCSEPL 256
            .|...:|:|.:.:.|.||..|...|..|:  ..|..:|...::.|   ..|        .|...:
Mosquito   268 TLERIAGIPEDKIVEAHGTFYTNHCLECK--IAYSLEFVKEKIFADEVPTC--------PCGGVI 322

  Fly   257 YDTIVHFG----ERGNVKWPLNWAGATANAQRADVILCLGSSLKV-----LKKYT---------- 302
            ...||.||    ||.::....::|       ..|:::.:|:||.|     |.:|.          
Mosquito   323 KPDIVFFGEGLPERFHMLPHQDFA-------ECDLLIIMGTSLTVQPFASLVEYVNDDCVRLLIN 380

  Fly   303 ----------WLWQM--------DRPARQRAKICVVNLQWTPKDAIASIKINGKCD--------- 340
                      :|..|        |.|..:|      ::.||           |.||         
Mosquito   381 RDKVGCNSFGFLRSMVFGEGLCFDLPGNRR------DVAWT-----------GNCDDGCFFLADQ 428

  Fly   341 ----QVMAQLMHLLHIPV----PVYTK----------EKDP-----------IFAHASLLMPEEL 376
                ..:.:|:...|..:    |:.|.          :.:|           :...|..|:||:.
Mosquito   429 LGWGDELRKLVETEHAKIKPIRPIATNAIAVPDGTVVDMEPTTDIHHTDDHCLVDDAECLLPEDE 493

  Fly   377 H 377
            |
Mosquito   494 H 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sirt7NP_651664.2 SIRT7 124..338 CDD:238701 65/284 (23%)
LOC1273019XP_311957.5 SIRT1 174..422 CDD:238699 66/281 (23%)

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