Protein Alignment CG11843 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 86/323 - (26%)
• Similarity: 127/323 - (39%)
• Gaps: 101/323 - (31%)

  Fly    50 GASIESRI----------------------------------IDNCRSYTPL-------IVGGHP 73
            |||::|||                                  |:.|.:...|       |:||..
Human   128 GASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTE 192

  Fly    74 AQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCLESERGEVNVVRLGELDFDSLDE 138
            |:...:|....|  |.:.:..    |||.||:..::||||||..|
Human   193 AEEGSWPWQVSL--RLNNAHH----CGGSLINNMWILTAAHCFRS-------------------- 231

  Fly   139 DAAPRDYM---------------VAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPACLPFQ 188
            ::.|||::               |...:.|..|:.....:||.||:|..:|.|....|..|||..
Human   232 NSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAA 296

  Fly   189 DER---SSDSFIAVGWGSTGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDG---NNQ 247
            .:.   .|.::: .|||:...|.....:|.:.:::...|.||..         |..::|   :..
Human   297 TQNIPPGSTAYV-TGWGAQEYAGHTVPELRQGQVRIISNDVCNA---------PHSYNGAILSGM 351

  Fly   248 LCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWI 309
            ||.| .:...|.|.|||||||:  ..:...::.:|||.|.|..||.|..||:||||..||.||
Human   352 LCAGVPQGGVDACQGDSGGPLV--QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	77/264 (29%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	6/17 (35%)
		Tryp_SPc	187..415	CDD:238113	77/264 (29%)