Protein Alignment CG11843 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 88/304 - (28%)
• Similarity: 130/304 - (42%)
• Gaps: 60/304 - (19%)

  Fly    43 EFGFLLP--GASIES--RIIDNCRS------------YTPL---IVGGHPAQPREFPHMA--RLG 86
            ||..|.|  |..:|.  :..:||.|            ..||   ||||....|..:|..|  .||
Human   174 EFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALG 238

  Fly    87 RRPDPSSRADWFCGGVLISERFVLTAAHCLESERGEVNVVRLGELDFDS-LDEDAAPRDY---MV 147
            .|..        |||.:::.|:|:|||||:.|.|    :.||......: |...:|.|.:   :|
Human   239 FRHT--------CGGSVLAPRWVVTAAHCMHSFR----LARLSSWRVHAGLVSHSAVRPHQGALV 291

  Fly   148 AGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPACLPFQDE---RSSDSFIAVGWGSTGLALK 209
            ...|.||.|......:|:.|::|..|:.|.......|||.:::   :.|..::: |||.|..:..
Human   292 ERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVS-GWGHTHPSHT 355

  Fly   210 PSAQLLK-VKLQRYGNWVCKKLLTRQVEEFPRGFDGNNQLCVG-SEMAQDTCNGDSGGPLLMYHR 272
            .|:.:|: ..:..:...:|...........||      .||.| .:...|.|.|||||||:
Human   356 YSSDMLQDTVVPLFSTQLCNSSCVYSGALTPR------MLCAGYLDGRADACQGDSGGPLV---- 410

  Fly   273 EYPC----MYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWIART 312
               |    .:.:||:.|.|..|..|..||:|.:|..:|.||..|
Human   411 ---CPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDT 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	76/258 (29%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	9/38 (24%)
		Tryp_SPc	217..448	CDD:214473	74/256 (29%)