DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11843 and F12

DIOPT Version :9

Sequence 1:	NP_001287578.1	Gene:	CG11843 / 43432	FlyBaseID:	FBgn0039630	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_067464.2	Gene:	F12 / 58992	MGIID:	1891012	Length:	597	Species:	Mus musculus

Alignment Length:	275	Identity:	82/275 - (29%)
Similarity:	115/275 - (41%)	Gaps:	59/275 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 IVGGHPAQPREFPHMARLGRRPDPSSRADW---FCGGVLISERFVLTAAHCLESERG--EVNVVR 127
            :|||..|.|...|::|.|          .|   ||.|.||:..:||||||||::...  |:.||
Mouse   355 VVGGLVALPGSHPYIAAL----------YWGNNFCAGSLIAPCWVLTAAHCLQNRPAPEELTVV- 408

  Fly   128 LGELDFDSLDEDAA-PRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEA-----VVFDLYKHPACLP 186
            ||:   |..::... .:...|..|..|.|:....:.||:.|::|.|:     .:...:..|.|||
Mouse   409 LGQ---DRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPHVQPVCLP 470

  Fly   187 FQDERSSDSFI--AVGWG---------STGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPR 240
            ......|::.:  ..|||         ||.|   ..||:..:.|.|..|               .
Mouse   471 SGAAPPSETVLCEVAGWGHQFEGAEEYSTFL---QEAQVPFIALDRCSN---------------S 517

  Fly   241 GFDGN----NQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYT 300
            ...|:    ..||.| .|...|.|.|||||||:...........:.|:.|.|..||....||:||
Mouse   518 NVHGDAILPGMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYT 582

  Fly   301 RVYPYLGWIARTLAT 315
            .|..||.||.:.:|:
Mouse   583 DVANYLAWIQKHIAS 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_001287578.1	Tryp_SPc	68..312	CDD:238113	81/270 (30%)
CG11843	NP_001287578.1	Tryp_SPc	68..309	CDD:214473	79/267 (30%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:278437
		KR	217..295	CDD:294073
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..338
		Tryp_SPc	354..591	CDD:214473	79/267 (30%)
		Tryp_SPc	355..594	CDD:238113	81/270 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960