Protein Alignment CG11843 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 95/326 - (29%)
• Similarity: 132/326 - (40%)
• Gaps: 50/326 - (15%)

  Fly     7 FSQLIVSLAC--------------VFGQQPDMDVVGSCSRYKKSVFEERIEFGFLLPGASIESRI 57
            |::.:...||              ..|...|:|||......::  ...|...|..|.|:.:....
Human   131 FTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQE--LRMRNSSGPCLSGSLVSLHC 193

  Fly    58 IDNCRSY-TPLIVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCLESERG 121
            :...:|. ||.:||...|....:|....:      .......|||.::...:|||||||......
Human   194 LACGKSLKTPRVVGVEEASVDSWPWQVSI------QYDKQHVCGGSILDPHWVLTAAHCFRKHTD 252

  Fly   122 EVN-VVRLGELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPACL 185
            ..| .||.|.....|....|..:..::.   .:|.|...   :||.|:||...:.|.....|.||
Human   253 VFNWKVRAGSDKLGSFPSLAVAKIIIIE---FNPMYPKD---NDIALMKLQFPLTFSGTVRPICL 311

  Fly   186 PFQDERSSDS--FIAVGWGST----GLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDG 244
            ||.||..:.:  ...:|||.|    |   |.|..||:..:|...:..|      ..::..:|...
Human   312 PFFDEELTPATPLWIIGWGFTKQNGG---KMSDILLQASVQVIDSTRC------NADDAYQGEVT 367

  Fly   245 NNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGW 308
            ...:|.| .|...|||.|||||| |||..:   .:.||||.|.|..||.|..||:||:|..||.|
Human   368 EKMMCAGIPEGGVDTCQGDSGGP-LMYQSD---QWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNW 428

  Fly   309 I 309
            |
Human   429 I 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	80/250 (32%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	12/67 (18%)
		Tryp_SPc	204..429	CDD:214473	78/249 (31%)