Protein Alignment CG11843 and PRSS2

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 81/261 - (31%)
• Similarity: 114/261 - (43%)
• Gaps: 40/261 - (15%)

  Fly    68 IVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCLESE-------RG-EVN 124
            ||||:..:....|:...|       :....||||.||||::|::|.||.:|.       || |.:
Human    24 IVGGYICEENSVPYQVSL-------NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYH 81

  Fly   125 --VVRLGELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPACLPF 187
              .|||||.:.:.|:.:  .:....|..|.||.|......:||.|:||:...|.:.......||.
Human    82 RIQVRLGEHNIEVLEGN--EQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPT 144

  Fly   188 QDERSSDSFIAVGWGST---GLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDGNNQLC 249
            ....:....:..|||:|   |.......|.|...:          |...:.|....|...||..|
Human   145 APPAAGTESLISGWGNTLSSGADYPDELQCLDAPV----------LSQAECEASYPGKITNNMFC 199

  Fly   250 VG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWIARTL 313
            || .|..:|:|.||||||::....       :.||.|.|..|.....||:||:||.|:.||..|:
Human   200 VGFLEGGKDSCQGDSGGPVVSNGE-------LQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTI 257

  Fly   314 A 314
            |
Human   258 A 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	79/257 (31%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	79/257 (31%)