Protein Alignment CG11843 and PROC

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 76/281 - (27%)
• Similarity: 110/281 - (39%)
• Gaps: 67/281 - (23%)

  Fly    53 IESRIIDNCRSYTPLIVGGHPAQPREFPHMARLGRRPDP----SSRADWFCGGVLISERFVLTAA 113
            ::.|:||.                    .|.|.|..|..    .|:....||.|||...:|||||
Human   303 VDPRLIDG--------------------KMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAA 347

  Fly   114 HCLESERGEVNVVRLGELDFD-----SLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEA 173
            ||::..:  ..:|||||.|..     .||.|       :.....||.|......:||.|:.|.:.
Human   348 HCMDESK--KLLVRLGEYDLRRWEKWELDLD-------IKEVFVHPNYSKSTTDNDIALLHLAQP 403

  Fly   174 VVFDLYKHPACLPFQD------ERSSDSFIAVGWGSTGLALKPSAQ-------LLKVKLQRYGNW 225
            ........|.|||...      .::....:..|||......|.:.:       .:|:.:..:..
Human   404 ATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNE- 467

  Fly   226 VCKKLLTRQVEEFPRGFDGNNQLCVG-SEMAQDTCNGDSGGPLL-MYHREYPCMYVVVGITSAGL 288
             |.::::..|.|        |.||.| ....||.|.||||||:: .:|.    .:.:||:.|.|.
Human   468 -CSEVMSNMVSE--------NMLCAGILGDRQDACEGDSGGPMVASFHG----TWFLVGLVSWGE 519

  Fly   289 SCGSPGIPGIYTRVYPYLGWI 309
            .||.....|:||:|..||.||
Human   520 GCGLLHNYGVYTKVSRYLDWI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	73/266 (27%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	75/276 (27%)