DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11843 and masp2

DIOPT Version :9

Sequence 1:	NP_001287578.1	Gene:	CG11843 / 43432	FlyBaseID:	FBgn0039630	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001116330.1	Gene:	masp2 / 560277	ZFINID:	ZDB-GENE-060130-154	Length:	684	Species:	Danio rerio

Alignment Length:	349	Identity:	92/349 - (26%)
Similarity:	150/349 - (42%)	Gaps:	74/349 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 CVF---GQQPDMDVVGSCSRYKKSVFEERI-----EFGFLLPGAS--------------IESRII 58
            ||.   |:.|  :|..:..:|..::::..|     ||..:..|||              :..:|.
Zfish   357 CVIVDCGEPP--EVCNATVKYTTTIYKSVIKYTCNEFYSMDVGASGVYTCAHDGYWRDALGGKIQ 419

  Fly    59 DNCRSYTPL----------IVGGHPAQPREFPH--MARLGRRPDPSSRADWFCGGV-LISERFVL 110
            ..|   .|:          ::||..|:..|.|.  |.|:|.:         |.||. |:|:.:||
Zfish   420 QIC---LPICGQPELKLSKVIGGENAEKNEIPWQVMIRMGTK---------FIGGASLLSDGWVL 472

  Fly   111 TAAHCLESERGEVNV-VRLGELDFDSLDEDAA---PRDYMVAGYIAHPGY--EDPQFYHDIGLVK 169
            ||||.::|.....|: :|:|.:...  |.:|.   |:...:     ||.|  ::..|.|||.|:|
Zfish   473 TAAHVVKSFEDSANLQLRMGTVKHH--DNEAVVGIPQKIFI-----HPQYHHDNVNFNHDIALIK 530

  Fly   170 LTEAVVFDLYKHPACLPFQDER----SSDSFIAVGWG----STGLALKPSAQLLKVKLQRYGNWV 226
            |...|.......|.|||.::||    ::|.....|||    :|......:.:.:.:.:..:.:
Zfish   531 LEYKVPVSKAVMPVCLPGREERFVLKANDVGKVSGWGVSNINTPALFSGNLKYVHLPVSNFND-- 593

  Fly   227 CKKLLTRQVEEFPRGFDGNNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSC 290
            ||......|....:.....|.:|.| |:..:|:|.||||||...:.::....: :.||.|.|..|
Zfish   594 CKTKYDSTVTSKGKLVVTENMICAGFSQGGKDSCQGDSGGPFAFFDKQSKSWF-IGGIVSWGHGC 657

  Fly   291 GSPGIPGIYTRVYPYLGWIARTLA 314
            ...|..|:||:|..||.||...::
Zfish   658 AQAGYYGVYTKVSNYLSWIEEVMS 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_001287578.1	Tryp_SPc	68..312	CDD:238113	77/261 (30%)
CG11843	NP_001287578.1	Tryp_SPc	68..309	CDD:214473	75/258 (29%)
masp2	NP_001116330.1	CUB	24..130	CDD:214483
		EGF_CA	134..176	CDD:214542
		CUB	180..289	CDD:278839
		CCP	296..357	CDD:214478	92/349 (26%)
		CCP	362..410	CDD:153056	10/49 (20%)
		Tryp_SPc	435..676	CDD:214473	75/259 (29%)
		Tryp_SPc	436..679	CDD:238113	77/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910