Protein Alignment CG11843 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 324
• Identity: 81/324 - (25%)
• Similarity: 131/324 - (40%)
• Gaps: 67/324 - (20%)

  Fly    18 FGQQPDMDVVGSCSRYKKSVFEERIE-FGFLLPGASIESRIIDNCR---------SYTPLIVGGH 72
            :..|...|..|:.|..|.:|....:: :..|....|..||::.:.|         .....||||.
Mouse   194 YSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGL 258

  Fly    73 PAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCLESERGE-------VNVVRLGE 130
            .|.|.::|....|      ..:....|||.:|:..:::|||||:|.....       ..::|...
Mouse   259 NASPGDWPWQVSL------HVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSL 317

  Fly   131 LDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVF-DLYKHPACLP---FQDER 191
            :.:.|        .:.|...|:||.|:.....:||.|:||...:.| ||.| |.|||   ...:.
Mouse   318 MFYGS--------RHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVK-PVCLPNPGMMLDL 373

  Fly   192 SSDSFIAVGWGST----------GLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDGNN 246
            ..:.:|: |||:|          ..|:.|..:..|..    ..::...|:|..:
Mouse   374 DQECWIS-GWGATYEKGKTSDVLNAAMVPLIEPSKCN----SKYIYNNLITPAM----------- 422

  Fly   247 QLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWI 309
             :|.| .:.:.|:|.|||||||:.....   ::.::|.||.|..|.....||:|..|..:..||
Mouse   423 -ICAGFLQGSVDSCQGDSGGPLVTLKNG---IWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWI 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	70/264 (27%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747	11/52 (21%)
		Tryp_SPc	254..485	CDD:238113	70/264 (27%)