Protein Alignment CG11843 and KLKB1

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 81/263 - (30%)
• Similarity: 121/263 - (46%)
• Gaps: 32/263 - (12%)

  Fly    59 DN--CRSYTPL-IVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCLES-E 119
            ||  |.:.|.. ||||..:...|:|....|..:......   .|||.||..::|||||||.:. .
Human   390 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRH---LCGGSLIGHQWVLTAAHCFDGLP 451

  Fly   120 RGEVNVVRLGELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPAC 184
            ..:|..:..|.|:...:.:| .|.. .:...|.|..|:..:..|||.|:||...:.:..::.|.|
Human   452 LQDVWRIYSGILNLSDITKD-TPFS-QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPIC 514

  Fly   185 LPFQDERSS--DSFIAVGWGSTGLALKPSAQLLKVKLQRYGNWVCKK-----LLTRQVEEFPRGF 242
            ||.:.:.|:  .:....|||.:....:....|.||.:....|..|:|     .:|:::
Human   515 LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRM------- 572

  Fly   243 DGNNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYL 306
                 :|.| .|..:|.|.|||||||:..|..   |:.:|||||.|..|.....||:||:|..|:
Human   573 -----VCAGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQPGVYTKVAEYM 629

  Fly   307 GWI 309
            .||
Human   630 DWI 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	77/251 (31%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519
		Tryp_SPc	402..632	CDD:238113	75/249 (30%)