Protein Alignment CG11843 and KLK2

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 92/286 - (32%)
• Similarity: 121/286 - (42%)
• Gaps: 73/286 - (25%)

  Fly    61 CRSYTPL----IVGG-------HPAQPREFPHMARLGRRPDPSSRADW-FCGGVLISERFVLTAA 113
            |....||    ||||       .|.|...:.|              .| .|||||:..::|||||
Human    14 CTGAVPLIQSRIVGGWECEKHSQPWQVAVYSH--------------GWAHCGGVLVHPQWVLTAA 64

  Fly   114 HCLESERGEVNVVRLGELD-FDSLDEDAAPRDYMVAGYIAHPGYE-----------DPQFYHDIG 166
            |||:..    :.|.||..: |:  .||...| ..|:....||.|.           |....||:.
Human    65 HCLKKN----SQVWLGRHNLFE--PEDTGQR-VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLM 122

  Fly   167 LVKLTE-AVVFDLYKHPACLPFQDERSSDSFIAVGWGSTGLALKPS-----AQLLKVKLQRYGNW 225
            |::|:| |.:.|:.| ...||.|:.....:..|.||||    ::|.     ..|..|.|....|.
Human   123 LLRLSEPAKITDVVK-VLGLPTQEPALGTTCYASGWGS----IEPEEFLRPRSLQCVSLHLLSND 182

  Fly   226 VCKKLLTRQVEEFPRGFDGNNQLCVGS-EMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLS 289
            :|.:..:.:|.||        .||.|. ...:|||.|||||||:       |..|:.||||.|..
Human   183 MCARAYSEKVTEF--------MLCAGLWTGGKDTCGGDSGGPLV-------CNGVLQGITSWGPE 232

  Fly   290 -CGSPGIPGIYTRVYPYLGWIARTLA 314
             |..|..|.:||:|..|..||..|:|
Human   233 PCALPEKPAVYTKVVHYRKWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	87/271 (32%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	87/271 (32%)