Protein Alignment CG11843 and KLK1

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 92/291 - (31%)
• Similarity: 131/291 - (45%)
• Gaps: 73/291 - (25%)

  Fly    50 GAS--IESRIIDNCRSYTPLIVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTA 112
            ||:  |:||           ||||...:....|..|.|      ...:.:.|||:|:..::||||
Human    16 GAAPPIQSR-----------IVGGWECEQHSQPWQAAL------YHFSTFQCGGILVHRQWVLTA 63

  Fly   113 AHCLESE----RGEVNVVRLGELDFDSLDEDAAPRDYMVAGYIAHPGYE-----------DPQFY 162
            |||:...    .|..|:       ||  ||:.| :...|:....|||:.           |..:.
Human    64 AHCISDNYQLWLGRHNL-------FD--DENTA-QFVHVSESFPHPGFNMSLLENHTRQADEDYS 118

  Fly   163 HDIGLVKLTEA--VVFDLYKHPACLPFQDERSSDSFIAVGWGSTGLALKPS-----AQLLKVKLQ 220
            ||:.|::|||.  .:.|..| ...||.::.....:.:|.||||    ::|.     ..|..|.|:
Human   119 HDLMLLRLTEPADTITDAVK-VVELPTEEPEVGSTCLASGWGS----IEPENFSFPDDLQCVDLK 178

  Fly   221 RYGNWVCKKLLTRQVEEFPRGFDGNNQLCVGS-EMAQDTCNGDSGGPLLMYHREYPCMYVVVGIT 284
            ...|..|||...::|.:|        .||||. |..:|||.|||||||:       |..|:.|:|
Human   179 ILPNDECKKAHVQKVTDF--------MLCVGHLEGGKDTCVGDSGGPLM-------CDGVLQGVT 228

  Fly   285 SAG-LSCGSPGIPGIYTRVYPYLGWIARTLA 314
            |.| :.||:|..|.:..||..|:.||..|:|
Human   229 SWGYVPCGTPNKPSVAVRVLSYVKWIEDTIA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	85/267 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	85/267 (32%)