Protein Alignment CG11843 and HPN

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 86/296 - (29%)
• Similarity: 115/296 - (38%)
• Gaps: 59/296 - (19%)

  Fly    49 PGASIESRIIDNC-RSYTPL--IVGGHPAQPREFPHMARLGRRP-DPSSRAD--WFCGGVLISER 107
            |.....:.|..:| |...|:  ||||....         |||.| ..|.|.|  ..|||.|:|..
Human   141 PRGRFLAAICQDCGRRKLPVDRIVGGRDTS---------LGRWPWQVSLRYDGAHLCGGSLLSGD 196

  Fly   108 FVLTAAHCLESERGEVNVVRLGELDFDSLDEDAAPRDYM--VAGYIAHPGY---EDP---QFYHD 164
            :|||||||.......::..|:    |......|:|....  |...:.|.||   .||   :..:|
Human   197 WVLTAAHCFPERNRVLSRWRV----FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSND 257

  Fly   165 IGLVKLTEAVVFDLYKHPACLPFQDERSSDSFI--AVGWGSTGLALKPSAQLLKVKLQRYGNWVC 227
            |.||.|:..:....|..|.|||...:...|..|  ..|||:|....:.:..|.:.::....|.||
Human   258 IALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVC 322

  Fly   228 KKLLTRQVEEFPRGFDGN----NQLCVG-SEMAQDTCNGDSGGPLLMYHREYPC--------MYV 279
            .          ...|.||    ...|.| .|...|.|.||||||       :.|        .:.
Human   323 N----------GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGP-------FVCEDSISRTPRWR 370

  Fly   280 VVGITSAGLSCGSPGIPGIYTRVYPYLGWIARTLAT 315
            :.||.|.|..|.....||:||:|..:..||.:.:.|
Human   371 LCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKT 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	80/269 (30%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	4/17 (24%)
		Tryp_SPc	163..400	CDD:238113	78/266 (29%)