Protein Alignment CG11843 and GZMK

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 90/282 - (31%)
• Similarity: 122/282 - (43%)
• Gaps: 48/282 - (17%)

  Fly    46 FLLPGASIESRIIDNCRSYTPLIVGGHPAQPREFPHMARL---GRRPDPSSRADWFCGGVLISER 107
            ||:.||.: :.:..|..     |:||....|...|.||.:   |..         .||||||..:
Human    11 FLIVGAYM-THVCFNME-----IIGGKEVSPHSRPFMASIQYGGHH---------VCGGVLIDPQ 60

  Fly   108 FVLTAAHC-LESERGEVNVVRLGELDFDSLDEDAAPRDYM-VAGYIAHPGY-EDPQFYHDIGLVK 169
            :||||||| ....:|:...|.||.   .||.::.|.:..: :..:|..... .||| .:||.|||
Human    61 WVLTAAHCQYRFTKGQSPTVVLGA---HSLSKNEASKQTLEIKKFIPFSRVTSDPQ-SNDIMLVK 121

  Fly   170 LTEAVVFDLYKHPACLPFQDE---RSSDSFIAVGWGSTGL-ALKPSAQLLKVKLQRYGNWVCKKL 230
            |..|.  .|.||...|..:.:   ||.......|||:|.. :|:||..|.:|.:......:|..
Human   122 LQTAA--KLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNS- 183

  Fly   231 LTRQVEEFPRG--FDGNNQLCVGSEMAQ-DTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGS 292
                 :.:..|  |...:.:|.|....| |:|.|||||||:       |..|...|.|.|..||.
Human   184 -----QSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLI-------CKGVFHAIVSGGHECGV 236

  Fly   293 PGIPGIYTRV-YPYLGWIARTL 313
            ...|||||.: ..|..||...|
Human   237 ATKPGIYTLLTKKYQTWIKSNL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	84/257 (33%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	84/257 (33%)