Protein Alignment CG11843 and GZMA

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 83/288 - (28%)
• Similarity: 120/288 - (41%)
• Gaps: 46/288 - (15%)

  Fly    41 RIEFGFLLPGASIESRII----DNCRSYTPLIVGGHPAQPREFPHMARLGRRPDPSSRADWFCGG 101
            |..:.||....|:...::    |.|..    |:||:...|...|:|..|      |......|.|
Human     2 RNSYRFLASSLSVVVSLLLIPEDVCEK----IIGGNEVTPHSRPYMVLL------SLDRKTICAG 56

  Fly   102 VLISERFVLTAAHCLESERGEV-----NVVRLGELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQF 161
            .||::.:|||||||..::|.:|     ::.|          |:...:..:|.....:|.|:....
Human    57 ALIAKDWVLTAAHCNLNKRSQVILGAHSITR----------EEPTKQIMLVKKEFPYPCYDPATR 111

  Fly   162 YHDIGLVKLTEAVVFDLYKHPACLPFQ--DERSSDSFIAVGWGSTGLALKPSAQLLKVKLQRYGN 224
            ..|:.|::|.|....:.|.....||.:  |.:........|||.|..:...|..|.:|.:.....
Human   112 EGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDR 176

  Fly   225 WVCKKLLTRQVEEFPRGFDGNNQLCVGS-EMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGL 288
            .||.   .|....| ....|.|.:|.|| ...:|:||||||.|||       |..|..|:||.||
Human   177 KVCN---DRNHYNF-NPVIGMNMVCAGSLRGGRDSCNGDSGSPLL-------CEGVFRGVTSFGL 230

  Fly   289 --SCGSPGIPGIYTRV-YPYLGWIARTL 313
              .||.|..||:|..: ..:|.||..|:
Human   231 ENKCGDPRGPGVYILLSKKHLNWIIMTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	76/254 (30%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	74/251 (29%)