Protein Alignment CG11843 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 81/265 - (30%)
• Similarity: 114/265 - (43%)
• Gaps: 52/265 - (19%)

  Fly    68 IVGGHPAQPREFPHMARL----GRRPDPSSRADWFCGGVLISERFVLTAAHCLESER-------- 120
            |:||..||...:|.:..|    ||      .....|||.|:.||:|||||||.:...
Human    78 IIGGTEAQAGAWPWVVSLQIKYGR------VLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAV 136

  Fly   121 -GEVNVVRLGELDFDSLDEDAAP--RDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHP 182
             |..|:            ....|  :...:...|.||.:....:.:||.|..|.:||.::.|..|
Human   137 IGTNNI------------HGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQP 189

  Fly   183 ACLPFQD----ERSSDSFIAVGWGSTGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFD 243
            .||||..    :.::..||: |||.|    |.......:......:::.:::...:     |.:.
Human   190 ICLPFDVFQILDGNTKCFIS-GWGRT----KEEGNATNILQDAEVHYISREMCNSE-----RSYG 244

  Fly   244 G---NNQLCVGSE-MAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYP 304
            |   |...|.|.| .|.|||.|||||||:.|..||. .:.|:||||.|..||..|.||:|.....
Human   245 GIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYK-RFFVMGITSYGHGCGRRGFPGVYIGPSF 308

  Fly   305 YLGWI 309
            |..|:
Human   309 YQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	81/265 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	81/265 (31%)