Protein Alignment CG11843 and F12

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 78/262 - (29%)
• Similarity: 107/262 - (40%)
• Gaps: 45/262 - (17%)

  Fly    68 IVGGHPAQPREFPHMARLGRRPDPSSRADW---FCGGVLISERFVLTAAHCLESERG--EVNVVR 127
            :|||..|.....|::|.|          .|   ||.|.||:..:||||||||:....  ::.||
Human   373 VVGGLVALRGAHPYIAAL----------YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVV- 426

  Fly   128 LGELDFDSLDEDAAP-RDYMVAGYIAHPGYEDPQFYHDIGLVKLTE-----AVVFDLYKHPACLP 186
            ||:   :..:....| :...|..|..|..:....:.||:.|::|.|     ..:...|..|.|||
Human   427 LGQ---ERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLP 488

  Fly   187 FQDERSSDSFI--AVGWGSTGLALKPSAQLLK------VKLQRYGNWVCKKLLTRQVEEFPRGFD 243
            ....|.|::.:  ..|||......:..|..|:      :.|:|     |...........|
Human   489 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLER-----CSAPDVHGSSILP---- 544

  Fly   244 GNNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLG 307
              ..||.| .|...|.|.|||||||:...:.......:.||.|.|..||....||:||.|..||.
Human   545 --GMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLA 607

  Fly   308 WI 309
            ||
Human   608 WI 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	78/262 (30%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	78/262 (30%)