Protein Alignment CG11843 and F7

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 97/351 - (27%)
• Similarity: 149/351 - (42%)
• Gaps: 76/351 - (21%)

  Fly     6 LFSQLIVSLACVFGQQPDMD-------VVGSCSRY-------KKSVFEERIEFGF--LLPGASIE 54
            |.|.|:.|       .||.|       ..|.|.:|       |:|.   |...|:  |..|.|..
Human   163 LCSALVPS-------SPDKDDQLICVNENGGCEQYCSDHTGTKRSC---RCHEGYSLLADGVSCT 217

  Fly    55 SRIIDNCRSYTPLIVGGHPAQPREFPHMARL-GRRPDPSSRADW----------FCGGVLISERF 108
            ..:...| ...|::...:.::|:     .|: |.:..|.....|          .|||.||:..:
Human   218 PTVEYPC-GKIPILEKRNASKPQ-----GRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIW 276

  Fly   109 VLTAAHCLESERGEVNVVR-LGELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTE 172
            |::||||.:..:...|::. |||.|....|.|...|  .||..|....|......|||.|::|.:
Human   277 VVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSR--RVAQVIIPSTYVPGTTNHDIALLRLHQ 339

  Fly   173 AVVFDLYKHPACLPFQDERS-SDSFIAV-------GW------GSTGLALKPSAQLLKVKLQRYG 223
            .||...:..|.|||   ||: |:..:|.       ||      |:|.|      :|:.:.:.|..
Human   340 PVVLTDHVVPLCLP---ERTFSERTLAFVRFSLVSGWGQLLDRGATAL------ELMVLNVPRLM 395

  Fly   224 NWVCKKLLTRQVEEFPRGFDGNNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAG 287
            ...|.: .:|:|.:.|...:  ...|.| |:.::|:|.||||||...::|.   .:.:.||.|.|
Human   396 TQDCLQ-QSRKVGDSPNITE--YMFCAGYSDGSKDSCKGDSGGPHATHYRG---TWYLTGIVSWG 454

  Fly   288 LSCGSPGIPGIYTRVYPYLGWIARTL 313
            ..|.:.|..|:||||..|:.|:.:.:
Human   455 QGCATVGHFGVYTRVSQYIEWLQKLM 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	78/270 (29%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	9/38 (24%)
		Tryp_SPc	242..478	CDD:238113	76/252 (30%)