Protein Alignment CG11843 and Prss12

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_032965.1
• Gene: Prss12 / 19142
• MGIID: 1100881
• Length: 761
• Species: Mus musculus
• Alignment Length: 260
• Identity: 87/260 - (33%)
• Similarity: 122/260 - (46%)
• Gaps: 39/260 - (15%)

  Fly    68 IVGGHPAQPREFPHMARLGRRPDPSSRAD--WFCGGVLISERFVLTAAHCLE--SERGEVNVVRL 128
            |:||:.:....:|..|.|..|   |:..|  ..||..|:|..:|||||||.:  ........||:
Mouse   517 IIGGNNSLRGAWPWQASLRLR---SAHGDGRLLCGATLLSSCWVLTAAHCFKRYGNNSRSYAVRV 578

  Fly   129 GELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKL----TEAVVFDLYKHPACLPFQD 189
            |  |:.:|..:...::..|...:.|..|...:..:||.||:|    .:......:..|||||...
Mouse   579 G--DYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDYDIALVRLQGPGEQCARLSTHVLPACLPLWR 641

  Fly   190 ER----SSDSFIAVGWGSTGLALKPSAQLLKVKL--QRYGNWVCKKLLTRQVEEFPRGFDGNNQL 248
            ||    :|:..| .|||.||.|...:.|...|.|  :|:    ||       |.:...|.| ..|
Mouse   642 ERPQKTASNCHI-TGWGDTGRAYSRTLQQAAVPLLPKRF----CK-------ERYKGLFTG-RML 693

  Fly   249 CVGS---EMAQDTCNGDSGGPLLMYHREYPC-MYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWI 309
            |.|:   :...|:|.|||||||:.   |.|. .:||.|:||.|..||....||:||||..::.||
Mouse   694 CAGNLQEDNRVDSCQGDSGGPLMC---EKPDESWVVYGVTSWGYGCGVKDTPGVYTRVPAFVPWI 755

  Fly   310  309
            Mouse   756  755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	87/260 (33%)
Prss12	NP_032965.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..87
		KR	83..159	CDD:214527
		SR	166..265	CDD:214555
		SR	273..372	CDD:214555
		SR	386..485	CDD:214555
		Zymogen activation region	505..516
		Tryp_SPc	517..758	CDD:238113	87/260 (33%)