DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11843 and Plau

DIOPT Version :9

Sequence 1:	NP_001287578.1	Gene:	CG11843 / 43432	FlyBaseID:	FBgn0039630	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_032899.1	Gene:	Plau / 18792	MGIID:	97611	Length:	433	Species:	Mus musculus

Alignment Length:	314	Identity:	90/314 - (28%)
Similarity:	127/314 - (40%)	Gaps:	70/314 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VVGSCSRYKKSVFEERIEFGFLLPGASIESRIIDNC--RSYTP--LIVGGHPAQPREFPHMARLG 86
            :|..||..||             |.:|::.:.. .|  ::..|  .||||...:....|..|.:.
Mouse   148 MVHDCSLSKK-------------PSSSVDQQGF-QCGQKALRPRFKIVGGEFTEVENQPWFAAIY 198

  Fly    87 RRPDPSSRADWFCGGVLISERFVLTAAHC-LESERGEVNVVRLGELDFDSLDEDAAPRD--YMVA 148
            ::....|...:.|||.|||..:|.:|||| ::..:.|..||.||:    |.:....|.:  :.|.
Mouse   199 QKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQ----SKESSYNPGEMKFEVE 259

  Fly   149 GYIAHPGY-EDPQFYH-DIGLVKLTEAVVFDLYKHPA------CLP--FQDERSSDSFIAVGWG- 202
            ..|.|..| ||...|| ||.|:|:..:.  .....|:      |||  |.|..........|:|
Mouse   260 QLILHEYYREDSLAYHNDIALLKIRTST--GQCAQPSRSIQTICLPPRFTDAPFGSDCEITGFGK 322

  Fly   203 -STGLALKP-SAQLLKVKL---------QRYGNWVCKKLLTRQVEEFPRGFDGNNQLCVGS-EMA 255
             |....|.| :.::..|||         ..||:.:..|:                 ||... |..
Mouse   323 ESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYKM-----------------LCAADPEWK 370

  Fly   256 QDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWI 309
            .|:|.|||||||:......|   .:.||.|.|..|.....||:||||..:|.||
Mouse   371 TDSCKGDSGGPLICNIEGRP---TLSGIVSWGRGCAEKNKPGVYTRVSHFLDWI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_001287578.1	Tryp_SPc	68..312	CDD:238113	81/268 (30%)
CG11843	NP_001287578.1	Tryp_SPc	68..309	CDD:214473	79/266 (30%)
Plau	NP_032899.1	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	35..58
		Kringle	71..152	CDD:333799	1/3 (33%)
		Connecting peptide	153..179		7/39 (18%)
		Tryp_SPc	180..424	CDD:238113	81/268 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960