DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11843 and svh-1

DIOPT Version :9

Sequence 1:	NP_001287578.1	Gene:	CG11843 / 43432	FlyBaseID:	FBgn0039630	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	314	Identity:	86/314 - (27%)
Similarity:	126/314 - (40%)	Gaps:	66/314 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LACVFGQQPDMDVVGSCS-RYKKSVFEERIEFGFLLPGASIESRIIDNCRSYTPLIVGGHPAQPR 77
            ::|:  .|..|.....|. ||                   :|....|..:|....:|||....|.
Worm   679 ISCI--SQNGMSSASQCGLRY-------------------VEVNARDAAKSRIARVVGGFETVPG 722

  Fly    78 EFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHCL-ESERGEVNVVRLGELDFDSLDEDAA 141
            .||..|.|..:...:..    ||..::.:..::|||||. |.||.....|.:|  |:|:...|..
Worm   723 AFPWTAALRNKATKAHH----CGASILDKTHLITAAHCFEEDERVSSYEVVVG--DWDNNQTDGN 781

  Fly   142 PRDYMVAGYIAHPGYEDPQFYHDIGLVKLT-EAVVFDLYKHPACLPFQD--ERSSDSFIAVGWGS 203
            .:.:.:.....:|.|:| .|.|||.::::. ..:.|:.|..|.|||.:|  .......:..||||
Worm   782 EQIFYLQRIHFYPLYKD-IFSHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGS 845

  Fly   204 TGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDGNNQLCVGSEMAQ------------ 256
            .||              ||    .::|....:....| ||..|...:.|.|::
Worm   846 MGL--------------RY----AERLQAALIPIINR-FDCVNSSQIYSSMSRSAFCAGYLEGGI 891

  Fly   257 DTCNGDSGGPLLMYHREYPCMYVVVGITSAGLSCGSPGIPGIYTRVYPYLGWIA 310
            |:|.||||||...  |.....:|:.|:.|.|..|.....|||||.|.|||.||:
Worm   892 DSCQGDSGGPFAC--RREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWIS 943

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_001287578.1	Tryp_SPc	68..312	CDD:238113	77/259 (30%)
CG11843	NP_001287578.1	Tryp_SPc	68..309	CDD:214473	75/256 (29%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	0/1 (0%)
		Tryp_SPc	713..945	CDD:238113	77/259 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910