Protein Alignment CG11843 and KLK8

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 84/279 - (30%)
• Similarity: 119/279 - (42%)
• Gaps: 50/279 - (17%)

  Fly    48 LPGASIESRIIDNCRSYTPLIVGGHPAQPREFPHMARL--GRRPDPSSRADWFCGGVLISERFVL 110
            ||.|:..||..::      .::|||..||...|..|.|  |::        ..|||||:...:||
Human    64 LPPAAGHSRAQED------KVLGGHECQPHSQPWQAALFQGQQ--------LLCGGVLVGGNWVL 114

  Fly   111 TAAHCLESERGEVNVVRLGELDFDSLDEDAAPRDYMVAGYIAHPGY-----EDPQFYHDIGLVKL 170
            |||||.:.:    ..||||  |....::|...::..|...|.||.|     ||..  ||:.|::|
Human   115 TAAHCKKPK----YTVRLG--DHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHN--HDLMLLQL 171

  Fly   171 TEAVVFDLYKHPACLPFQDERSSDSFIAVGWGSTGLALKPSAQLL---KVKLQRYGNWVCKKLLT 232
            .:.........|..|.....:........|||:.....:.....|   :||:  :....|:....
Human   172 RDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKI--FPQKKCEDAYP 234

  Fly   233 RQVEEFPRGFDGNNQLCVGSEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGLS-CGSPGIP 296
            .|:.      ||  .:|.||....|||.|||||||:       |...:.||||.|.. ||....|
Human   235 GQIT------DG--MVCAGSSKGADTCQGDSGGPLV-------CDGALQGITSWGSDPCGRSDKP 284

  Fly   297 GIYTRVYPYLGWIARTLAT 315
            |:||.:..||.||.:.:.:
Human   285 GVYTNICRYLDWIKKIIGS 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	79/254 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	77/252 (31%)