Protein Alignment CG11843 and PRSS21

DIOPT Version :10

• Sequence 1: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 88/276 - (31%)
• Similarity: 127/276 - (46%)
• Gaps: 48/276 - (17%)

  Fly    62 RSYTPLIVGGHPAQPREFPHMARLGRRPDPSSRADW---FCGGVLISERFVLTAAHCLE--SERG 121
            |..|..||||..|:         |||.|...|...|   .||..|:|.|:.||||||.|  |:..
Human    36 RVITSRIVGGEDAE---------LGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLS 91

  Fly   122 EVN--VVRLGEL----DFDSLDEDAAPRDYMVAGYIAHPGY--EDPQFYHDIGLVKLTEAVVFDL 178
            :.:  :|:.|:|    .|.||  .|....|.|:.....|.|  ..|   :||.||||:..|.:..
Human    92 DPSGWMVQFGQLTSMPSFWSL--QAYYTRYFVSNIYLSPRYLGNSP---YDIALVKLSAPVTYTK 151

  Fly   179 YKHPACL---PFQDERSSDSFIAVGWG--STGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEF 238
            :..|.||   .|:.|..:|.:: .|||  ....||.....|.:|::....|.:|..|..:.  .|
Human   152 HIQPICLQASTFEFENRTDCWV-TGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY--SF 213

  Fly   239 PRGFDGNNQLCVG-SEMAQDTCNGDSGGPLLMYHREYPC----MYVVVGITSAGLSCGSPGIPGI 298
            .:...| :.:|.| ::..:|.|.|||||||       .|    ::..:|:.|.|:.||.|..||:
Human   214 RKDIFG-DMVCAGNAQGGKDACFGDSGGPL-------ACNKNGLWYQIGVVSWGVGCGRPNRPGV 270

  Fly   299 YTRVYPYLGWIARTLA 314
            ||.:..:..||.:.:|
Human   271 YTNISHHFEWIQKLMA 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	85/266 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	85/265 (32%)