DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11842 and CG18754

DIOPT Version :9

Sequence 1:	NP_651662.1	Gene:	CG11842 / 43431	FlyBaseID:	FBgn0039629	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	71/225 - (31%)
Similarity:	97/225 - (43%)	Gaps:	35/225 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 RHVLTAAHC---HYSPQGSVNI--ARLGDLEFD--TNNDDADPEDFDVKDFTAHPEF-SYPAIY- 166
            |:|||||||   .|..|..:.:  .|||:...|  |:.......|.:|...|.|..| |....|
  Fly   133 RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYR 197

  Fly   167 NDISVVRLSRPVTFNDYKHPACL-----PFDDGRLGTSFIAIGWGQLEIVPRTENKKL--QKVKL 224
            |||:::||..||.:.....|.||     |..|..|..|    ||.     |...::.|  ..||.
  Fly   198 NDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQIS----GWD-----PTKSSQTLITSTVKE 253

  Fly   225 YNYGTRCRITADRNDELPEGYNATTQLCIGSNEHKDTCNGDSGGPVL-IYHMDYPCMYHVMGITS 288
            .|       .||..:..| .:.:.:|:|.|.....|||.|.||.||: |..........:.||.|
  Fly   254 RN-------PADCLNRYP-SFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIAS 310

  Fly   289 IGVA-CDTPDLPAMYTRVHFYLDWIKQQLA 317
            .|.. |.:..:|.:||::..:.:|||..||
  Fly   311 YGQQYCYSAGIPGVYTKIGHFSEWIKANLA 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	69/221 (31%)
CG11842	NP_651662.1	Tryp_SPc	73..312	CDD:214473	66/218 (30%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/221 (31%)
		Tryp_SPc	108..335	CDD:214473	66/218 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940