DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11842 and F12

DIOPT Version :9

Sequence 1:	NP_651662.1	Gene:	CG11842 / 43431	FlyBaseID:	FBgn0039629	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_067464.2	Gene:	F12 / 58992	MGIID:	1891012	Length:	597	Species:	Mus musculus

Alignment Length:	261	Identity:	73/261 - (27%)
Similarity:	108/261 - (41%)	Gaps:	35/261 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 IIGGGPAVPKEFPHAARLGHKDENGEVEW---FCGGTLISDRHVLTAAHC-HYSPQGSVNIARLG 133
            ::||..|:|...|:.|.|         .|   ||.|:||:...||||||| ...|........||
Mouse   355 VVGGLVALPGSHPYIAAL---------YWGNNFCAGSLIAPCWVLTAAHCLQNRPAPEELTVVLG 410

  Fly   134 DLEFDTNNDDAD-PEDFDVKDFTAHPEFSYPAIYNDISVVRLSRPVT-----FNDYKHPACLPFD 192
            .   |.:|...: .:...|:.:..|..||.....:|::::||....|     .:.:..|.|||
Mouse   411 Q---DRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPHVQPVCLP-- 470

  Fly   193 DGRLGTSFIAI----GWGQLEIVPRTENKKLQKVKL-YNYGTRCRITADRNDELPEGYNATTQLC 252
            .|....|...:    |||.........:..||:.:: :....||..:....|.:..|     .||
Mouse   471 SGAAPPSETVLCEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAILPG-----MLC 530

  Fly   253 IGSNE-HKDTCNGDSGGPVLIYHMDYPCMYHVMGITSIGVACDTPDLPAMYTRVHFYLDWIKQQL 316
            .|..| ..|.|.||||||::...........:.|:.|.|..|...:.|.:||.|..||.||::.:
Mouse   531 AGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLAWIQKHI 595

  Fly   317 A 317
            |
Mouse   596 A 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	72/257 (28%)
CG11842	NP_651662.1	Tryp_SPc	73..312	CDD:214473	70/254 (28%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:278437
		KR	217..295	CDD:294073
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..338
		Tryp_SPc	354..591	CDD:214473	70/254 (28%)
		Tryp_SPc	355..594	CDD:238113	72/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960