Protein Alignment CG11842 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_651662.1
• Gene: CG11842 / 43431
• FlyBaseID: FBgn0039629
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 85/318 - (26%)
• Similarity: 126/318 - (39%)
• Gaps: 80/318 - (25%)

  Fly    27 QDSDIARTCTAYKRSVWEETSEFSFLIENAPIIYKTLDKCTSYA-------PLIIGGGPAVPKEF 84
            ||.|:.        .:.|.:.|......:.|.:..:|......|       |.::|...|....:
Human   160 QDLDVV--------EITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSW 216

  Fly    85 PHAARLGHKDENGEVEWFCGGTLISDRHVLTAAHCHYSPQG-----------------SVNIARL 132
            |....:.:..::     .|||:::....|||||||......                 |:.:|::
Human   217 PWQVSIQYDKQH-----VCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKI 276

  Fly   133 GDLEFDTNNDDADPEDFDVKDFTAHPEFSYPAIYNDISVVRLSRPVTFNDYKHPACLPFDDGRL- 196
            ..:||    :...|:|                  |||::::|..|:||:....|.||||.|..|
Human   277 IIIEF----NPMYPKD------------------NDIALMKLQFPLTFSGTVRPICLPFFDEELT 319

  Fly   197 -GTSFIAIGWGQLEIVPRTENKKLQKVKLYNY-----GTRCRITADRNDELPEGYNATTQLCIGS 255
             .|....||||    ..:....|:..:.|...     .|||..     |:..:|......:|.|.
Human   320 PATPLWIIGWG----FTKQNGGKMSDILLQASVQVIDSTRCNA-----DDAYQGEVTEKMMCAGI 375

  Fly   256 NE-HKDTCNGDSGGPVLIYHMDYPCMYHVMGITSIGVACDTPDLPAMYTRVHFYLDWI 312
            .| ..|||.|||||| |:|..|   .:||:||.|.|..|..|..|.:||:|..||:||
Human   376 PEGGVDTCQGDSGGP-LMYQSD---QWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	76/265 (29%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	8/44 (18%)
		Tryp_SPc	204..429	CDD:214473	74/264 (28%)