Protein Alignment CG11842 and GZMK

DIOPT Version :10

• Sequence 1: NP_651662.1
• Gene: CG11842 / 43431
• FlyBaseID: FBgn0039629
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 86/296 - (29%)
• Similarity: 110/296 - (37%)
• Gaps: 68/296 - (22%)

  Fly    47 SEFS--FLIENAPIIYKTLDKCTSYAPLIIGGGPAVPKEFPHAARL---GHKDENGEVEWFCGGT 106
            |.||  |||..|   |.| ..|.:..  ||||....|...|..|.:   ||.        .|||.
Human     5 SSFSLFFLIVGA---YMT-HVCFNME--IIGGKEVSPHSRPFMASIQYGGHH--------VCGGV 55

  Fly   107 LISDRHVLTAAHCHYS-PQGSVNIARLGDLEFDTNNDDADPEDFDVKDFTAHPEFSYPAIYNDIS 170
            ||..:.|||||||.|. .:|......||......|  :|..:..::|.|......:.....|||.
Human    56 LIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKN--EASKQTLEIKKFIPFSRVTSDPQSNDIM 118

  Fly   171 VVRLSRPVTFNDYKHPACLPFDDG---RLGTSFIAIGWGQL------------EIVPRTENKKLQ 220
            :|:|......|  ||...|.....   |.||.....|||..            |:.....::||.
Human   119 LVKLQTAAKLN--KHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLC 181

  Fly   221 KVKLYNYGTRCRITADRNDELPEGYNATTQLCIG-SNEHKDTCNGDSGGPVL---IYHMDYPCMY 281
            ..:.| |.....||.|             .:|.| :...||:|.||||||::   ::|
Human   182 NSQSY-YNGDPFITKD-------------MVCAGDAKGQKDSCKGDSGGPLICKGVFH------- 225

  Fly   282 HVMGITSIGVACDTPDLPAMYTRV-HFYLDWIKQQL 316
               .|.|.|..|.....|.:||.: ..|..|||..|
Human   226 ---AIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	75/265 (28%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	75/265 (28%)