DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11842 and Plau

DIOPT Version :9

Sequence 1:	NP_651662.1	Gene:	CG11842 / 43431	FlyBaseID:	FBgn0039629	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032899.1	Gene:	Plau / 18792	MGIID:	97611	Length:	433	Species:	Mus musculus

Alignment Length:	272	Identity:	77/272 - (28%)
Similarity:	119/272 - (43%)	Gaps:	50/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 IIGGGPAVPKEFPHAARLGHKDENGEVEWF-CGGTLISDRHVLTAAHCHYS-PQGSVNIARLGDL 135
            |:||.....:..|..|.:..|::.|....| |||:|||...|.:||||... |:....:..||..
Mouse   180 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQS 244

  Fly   136 EFDTNNDDADPED--FDVKDFTAHPEFSYP--AIYNDISVVRL----------SRPVTFNDYKHP 186
            :..:.|    |.:  |:|:....|..:...  |.:|||:::::          ||.:      ..
Mouse   245 KESSYN----PGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSI------QT 299

  Fly   187 ACLP--FDDGRLGTSFIAIGWGQLE----IVPRTENKKLQKVKLYNYGTRCRITADRNDELPEGY 245
            .|||  |.|...|:.....|:|:..    :.|:  |.|:..|||.:: .:|.        .|..|
Mouse   300 ICLPPRFTDAPFGSDCEITGFGKESESDYLYPK--NLKMSVVKLVSH-EQCM--------QPHYY 353

  Fly   246 NAT---TQLCIGSNEHK-DTCNGDSGGPVLIYHMDYPCMYHVMGITSIGVACDTPDLPAMYTRVH 306
            .:.   ..||....|.| |:|.||||||::......|.:   .||.|.|..|...:.|.:||||.
Mouse   354 GSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTL---SGIVSWGRGCAEKNKPGVYTRVS 415

  Fly   307 FYLDWIKQQLAK 318
            .:||||:..:.:
Mouse   416 HFLDWIQSHIGE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	77/267 (29%)
CG11842	NP_651662.1	Tryp_SPc	73..312	CDD:214473	75/264 (28%)
Plau	NP_032899.1	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	35..58
		Kringle	71..152	CDD:333799
		Connecting peptide	153..179
		Tryp_SPc	180..424	CDD:238113	77/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050