DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11842 and Plat

DIOPT Version :9

Sequence 1:	NP_651662.1	Gene:	CG11842 / 43431	FlyBaseID:	FBgn0039629	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	363	Identity:	94/363 - (25%)
Similarity:	142/363 - (39%)	Gaps:	100/363 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IVQLGAVLLVSFVAWASAQ--------------DSDIARTCTAYK--RSVWEETSEFSFLIENAP 57
            ||.:|.    |:.||.:..              |.|....|...|  :..||
Mouse   240 IVLMGK----SYTAWRTNSQALGLGRHNYCRNPDGDARPWCHVMKDRKLTWE------------- 287

  Fly    58 IIYKTLDKCTSYA------P--LIIGGGPAVPKEFPHAARLGHKDENGEVEWF-CGGTLISDRHV 113
              |..:..|::..      |  .|.||........|..|.:..|::....|.| |||.|||...|
Mouse   288 --YCDMSPCSTCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWV 350

  Fly   114 LTAAHC---HYSPQG-SVNIARL-----GDLEFDTNNDDADPEDFDVKDFTAHPEFSYPAIYNDI 169
            |:||||   .:.|.. .|.:.|.     |:.|          :.|:::.:..|.||......|||
Mouse   351 LSAAHCFLERFPPNHLKVVLGRTYRVVPGEEE----------QTFEIEKYIVHEEFDDDTYDNDI 405

  Fly   170 SVVRL----SRPVTFNDYKHPACLPFDDGRL--GTSFIAIGWGQLEIVPRTENKKLQK--VKLYN 226
            ::::|    .:....:.....||||..:.:|  .|.....|:|:.|......:.:|::  |:||.
Mouse   406 ALLQLRSQSKQCAQESSSVGTACLPDPNLQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYP 470

  Fly   227 YGTRCRITADRNDELPEGYNAT---TQLCI------GSNEHKDTCNGDSGGPVLIYHMDYPCMYH 282
             .:||     .:..|   :|.|   ..||.      |:.:..|.|.||||||::       ||.:
Mouse   471 -SSRC-----TSQHL---FNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLV-------CMIN 519

  Fly   283 ----VMGITSIGVACDTPDLPAMYTRVHFYLDWIKQQL 316
                :.||.|.|:.|...|:|.:||:|..|||||...:
Mouse   520 KQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWIHDNM 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	79/272 (29%)
CG11842	NP_651662.1	Tryp_SPc	73..312	CDD:214473	77/269 (29%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	13/73 (18%)
		Tryp_SPc	311..556	CDD:238113	78/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050