Protein Alignment CG11842 and PRSS21

DIOPT Version :10

• Sequence 1: NP_651662.1
• Gene: CG11842 / 43431
• FlyBaseID: FBgn0039629
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 120/292 - (41%)
• Gaps: 90/292 - (30%)

  Fly    73 IIGGGPAVPKEFPHAARLGHKDENGEVEWFCGGTLISDRHVLTAAHCHYSPQGSVNIARLGDLEF 137
            |:||..|....:|....|...|.:     .||.:|:|.|..||||||                 |
Human    42 IVGGEDAELGRWPWQGSLRLWDSH-----VCGVSLLSHRWALTAAHC-----------------F 84

  Fly   138 DTNNDDADPEDFDVK--DFTAHPEF-SYPAIYN-------------------DISVVRLSRPVTF 180
            :|.:|.:||..:.|:  ..|:.|.| |..|.|.                   ||::|:||.|||:
Human    85 ETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149

  Fly   181 NDYKHPACL-----PFDDGRLGTSFIAIGWGQL---EIVPRTENKKLQKVKLYN----------Y 227
            ..:..|.||     .|::   .|.....|||.:   |.:|.....:..:|.:.|          |
Human   150 TKHIQPICLQASTFEFEN---RTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211

  Fly   228 GTRCRITADRNDELPEGYNATTQLCIGSNE-HKDTCNGDSGGPVLIYHMDYPC----MYHVMGIT 287
            ..|..|..|             .:|.|:.: .||.|.||||||:       .|    :::.:|:.
Human   212 SFRKDIFGD-------------MVCAGNAQGGKDACFGDSGGPL-------ACNKNGLWYQIGVV 256

  Fly   288 SIGVACDTPDLPAMYTRVHFYLDWIKQQLAKN 319
            |.||.|..|:.|.:||.:..:.:||::.:|::
Human   257 SWGVGCGRPNRPGVYTNISHHFEWIQKLMAQS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	77/286 (27%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	77/285 (27%)