Protein Alignment CG11841 and PRSS27

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 78/289 - (26%)
• Similarity: 120/289 - (41%)
• Gaps: 73/289 - (25%)

  Fly    65 CHGS----------RP----LIVDGTPAEPKEFPFAARLGHRKTNNEIKWFCGGTLISNRLVLTA 115
            |.||          ||    .:|.|...:..|:|:...:....::     ||||:||:.:.||||
Human    14 CFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSH-----FCGGSLIAEQWVLTA 73

  Fly   116 AHCFFSEHGEVNV--VRLGELEFDTDTDDAEPEDFGVLA----LKAHPGFENPQLYNDIGIVQLD 174
            ||| |....|.::  |.||..:.      .:|....:.|    ::::|.::......|:.:|:|:
Human    74 AHC-FRNTSETSLYQVLLGARQL------VQPGPHAMYARVRQVESNPLYQGTASSADVALVELE 131

  Fly   175 REVKFNRYKHPACLP-----FDDGEQHESFIAIGWG---------QKKFAQKESKKLLKVQLQGY 225
            ..|.|..|..|.|||     |:.|   .:....|||         :.:..||.:..::..
Human   132 APVPFTNYILPVCLPDPSVIFETG---MNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDT----- 188

  Fly   226 KDRCVSSVDANDELPNGYEPKS----QLCIGSRD-NKDTCNGDSGGPVLAYHKDLACM----YHV 281
             .:|......:.|.  ||:||:    .||.|..: .||.|.||||||       |.|:    :..
Human   189 -PKCNLLYSKDTEF--GYQPKTIKNDMLCAGFEEGKKDACKGDSGGP-------LVCLVGQSWLQ 243

  Fly   282 MGITSAGITCSTPDIPSAYTRVHYFLNWI 310
            .|:.|.|..|:..:.|..|.||....|||
Human   244 AGVISWGEGCARQNRPGVYIRVTAHHNWI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	73/268 (27%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	73/267 (27%)