Protein Alignment CG11841 and PRSS22

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 70/279 - (25%)
• Similarity: 117/279 - (41%)
• Gaps: 81/279 - (29%)

  Fly    72 IVDGTPAEPKEFPFAARLGHRKTNNEIKWFCGGTLISNRLVLTAAHCF---------FSEHGEVN 127
            :|.|..:...|:|:...:....|::     |.|:|:::|.|:||||||         ||
Human   158 VVGGEDSTDSEWPWIVSIQKNGTHH-----CAGSLLTSRWVITAAHCFKDNLNKPYLFS------ 211

  Fly   128 VVRLGELEFDTDTDDAEPEDFGVLALKAHPGFENPQLYN-------DIGIVQLDREVKFNRYKHP 185
             |.||  .:......:..:..||..::.||      :|:       ||.:|:|:|.::|:....|
Human   212 -VLLG--AWQLGNPGSRSQKVGVAWVEPHP------VYSWKEGACADIALVRLERSIQFSERVLP 267

  Fly   186 ACLPFDDGEQH-----ESFIAIGWGQKK----FAQKESKKLLKVQLQGYKDRCVSSVDANDELPN 241
            .|||  |...|     ..:|: |||..:    ....::.:.|||.:          :|:  |:.:
Human   268 ICLP--DASIHLPPNTHCWIS-GWGSIQDGVPLPHPQTLQKLKVPI----------IDS--EVCS 317

  Fly   242 -------GYEP--KSQLCIGSRD-NKDTCNGDSGGPVLAYHKDLACM----YHVMGITSAGITCS 292
                   |..|  :..||.|..: .:|.|.||||||       |.|.    :.:.||.|.|..|:
Human   318 HLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGP-------LMCQVDGAWLLAGIISWGEGCA 375

  Fly   293 TPDIPSAYTRVHYFLNWIK 311
            ..:.|..|..:....:|::
Human   376 ERNRPGVYISLSAHRSWVE 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	70/277 (25%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	70/279 (25%)