DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11841 and F12

DIOPT Version :9

Sequence 1:	NP_651661.1	Gene:	CG11841 / 43430	FlyBaseID:	FBgn0039628	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_067464.2	Gene:	F12 / 58992	MGIID:	1891012	Length:	597	Species:	Mus musculus

Alignment Length:	260	Identity:	80/260 - (30%)
Similarity:	116/260 - (44%)	Gaps:	34/260 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 IVDGTPAEPKEFPFAARL--GHRKTNNEIKWFCGGTLISNRLVLTAAHCFFSEHG--EVNVVRLG 132
            :|.|..|.|...|:.|.|  |    ||    ||.|:||:...|||||||..:...  |:.|| ||
Mouse   355 VVGGLVALPGSHPYIAALYWG----NN----FCAGSLIAPCWVLTAAHCLQNRPAPEELTVV-LG 410

  Fly   133 ELEFDTDTDDAE-PEDFGVLALKAHPGFENPQLYNDIGIVQLDREVKFNR------YKHPACLPF 190
            :   |......| .:...|.:.:.|.||.:....:|:.:::| :|.|.|.      :..|.|||.
Mouse   411 Q---DRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRL-QESKTNSCAILSPHVQPVCLPS 471

  Fly   191 DDGEQHESFI--AIGWG-QKKFAQKESKKLLKVQLQGYK-DRCVSSVDANDELPNGYEPKSQLCI 251
            ......|:.:  ..||| |.:.|::.|..|.:.|:.... |||.:|....|.:..|     .||.
Mouse   472 GAAPPSETVLCEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAILPG-----MLCA 531

  Fly   252 GSRD-NKDTCNGDSGGPVLAYHKDLACMYHVMGITSAGITCSTPDIPSAYTRVHYFLNWIKGELA 315
            |..: ..|.|.||||||::...........:.|:.|.|..|...:.|..||.|..:|.||:..:|
Mouse   532 GFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLAWIQKHIA 596

Fly 316 315
Mouse 597 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	78/254 (31%)
CG11841	NP_651661.1	Tryp_SPc	72..310	CDD:214473	77/253 (30%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:278437
		KR	217..295	CDD:294073
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..338
		Tryp_SPc	354..591	CDD:214473	77/253 (30%)
		Tryp_SPc	355..594	CDD:238113	79/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960