Protein Alignment CG11841 and KLK1

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 68/312 - (21%)
• Similarity: 98/312 - (31%)
• Gaps: 134/312 - (42%)

  Fly    20 NCSTNR---PQVTPVCGLISPVCEHCHRRIDAFDENAPPKVIEYVIKTDLDPEPLDYDPLNVGDM 81
            :|.::.   |..||....||         |||....| ||:.:  ||.:          |:.||.
Human    18 SCKSSERSLPDCTPHPNSIS---------IDAGPRQA-PKIAQ--IKRN----------LSYGDN 60

  Fly    82 SDPMGD-------DVKSEDDSEEPACIYVTKIVKRRGRRKASDEPVRSRAARRPGRPKLKVEPKK 139
            |||..:       |...|..|..||                  ||.:..|.||.|...||
Human    61 SDPALEASSLPPPDPWLETSSSSPA------------------EPAQPGACRRDGYWFLK----- 102

  Fly   140 ARKSFSSLREEKTSLDEGSSC----ENEADHLDER---------------PSSEKERFSSQDEDN 185
                   |.:.:|...||..|    |.:.::|.|.               .|.:.::|....|.|
Human   103 -------LLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQN 160

  Fly   186 --------------SKFTDL------DSDLDDDEALDH------------EEEEEEES------- 211
                          :.|.||      |..:..|| |.|            |:.:||:.
Human   161 LNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDE-LYHLKANSWQLVETPEKRKEEKKPPPPVPK 224

  Fly   212 ---------ALDEEVDEHTNSGEEPRKR-GRPKRAA---RGATSKSPKQCEV 250
                     :.|:..|......:|.||| ...||||   :.:.::|....|:
Human   225 KPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEI 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	54/257 (21%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	61/284 (21%)