Protein Alignment CG11841 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 85/291 - (29%)
• Similarity: 125/291 - (42%)
• Gaps: 66/291 - (22%)

  Fly    57 ITYETVDSCHGSRPL------IVDGTPAEPKEFPFAARL--GHRKTNNEIKWFCGGTLISNRLVL 113
            :|...:..| |:||.      :|.|..|...|.|:...|  |.|.       |||.|::.:|.:|
Human   518 VTVPKLQEC-GARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRH-------FCGATVVGDRWLL 574

  Fly   114 TAAHCFFSEHGEVNVVR----------LGELEFDTDTDDAEPEDFGVLALKAHPGFENPQLYN-D 167
            :|||||  .|.:|..||          ||          ..|...|:..:..||.: ||.:.: |
Human   575 SAAHCF--NHTKVEQVRAHLGTASLLGLG----------GSPVKIGLRRVVLHPLY-NPGILDFD 626

  Fly   168 IGIVQLDREVKFNRYKHPACLP-----FDDGEQHESFIAIGWGQKKFAQKESKKLLKVQLQGYKD 227
            :.:::|...:.||:|..|.|||     |..|.:   .:..|||..:.......:||:....|..|
Human   627 LAVLELASPLAFNKYIQPVCLPLAIQKFPVGRK---CMISGWGNTQEGNATKPELLQKASVGIID 688

  Fly   228 RCVSSVDANDELPNGYEPKSQLCIGSRDNK-DTCNGDSGGPVLAYHKDLAC-----MYHVMGITS 286
            :...||..|..|.:     ..:|.|..:.| |:|.||||||       |||     ::::.||.|
Human   689 QKTCSVLYNFSLTD-----RMICAGFLEGKVDSCQGDSGGP-------LACEEAPGVFYLAGIVS 741

  Fly   287 AGITCSTPDIPSAYTRVHYFLNWIKGELAKQ 317
            .||.|:....|..|||:.....||...::.|
Human   742 WGIGCAQVKKPGVYTRITRLKGWILEIMSSQ 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	78/262 (30%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113	79/264 (30%)
		Pneumo_att_G	<717..>867	CDD:114270	23/63 (37%)
		Tryp_SPc	861..1087	CDD:238113